Can pertussis syndrome be treated?

Whooping cough is a common cough symptom and falls into the category of severe cold symptoms. It has a great impact on the patient's health and can cause various discomfort symptoms in the patient. The most common one is constant coughing. Long-term coughing affects lung function. It can easily lead to serious lung complications in patients. Let’s take a look at whether whooping cough syndrome can be treated? I hope everyone can understand.

1. General treatment: Isolate the patient according to respiratory infectious diseases, keep the room quiet, fresh air and appropriate temperature, pay attention to avoid factors that induce spasmodic cough in children, eat nutritious and easily digestible food, and pay attention to supplement various vitamins and calcium supplements. Sedatives can reduce spasmodic coughs caused by fear, anxiety, and irritability in children, while ensuring sleep. Children can take promethazine (phenergan) 1m/kg each time, phenobarbital, etc. If the cough is severe, you can use cough suppressants. If the sputum is thick, you can use nebulizer inhalation. If convulsions occur, use drugs such as diazepam, compound chlorpromazine or phenobarbital to stop the convulsions. When a baby has severe coughing spasm, he or she should be supervised by someone. In case of suffocation, suction the phlegm or perform artificial respiration and oxygen in time. If cerebral edema occurs, dehydration treatment should be carried out in time to prevent brain herniation.

2. Antimicrobial treatment: The use of antibiotics during the catarrhal stage can alleviate or even prevent spasmodic cough. However, if used after entering the spasmodic cough stage, it will not shorten the clinical course of whooping cough. However, it can shorten the bacterial excretion period and prevent secondary infection. Erythromycin is the first choice. Bordetella pertussis is sensitive to erythromycin and can penetrate into respiratory secretions to reach effective concentrations. The dosage is 30-50 mg/kg per day, orally or intravenously. One course of treatment is 7 to 14 days. In recent years, some new macrolide antibiotics such as roxithromycin are taken orally at a daily dose of 5 to 10 mg/kg in two divided doses, with a course of treatment of 7 to 10 days. Azithromycin is taken at a dose of 10 mg/kg per day, once a day, for a course of 3 days.

The latter two have the advantages of strong antibacterial effect and fewer gastrointestinal reactions, and can be selected as appropriate. Ampicillin has poor clinical efficacy. Although chloramphenicol has better efficacy, it may occasionally cause granulocytopenia.