Have you heard of immunotherapy for kidney cancer?

The cause of kidney cancer is unknown. The treatment of kidney cancer is mainly surgical resection. The effects of radiotherapy, chemotherapy, and immunotherapy are not satisfactory and uncertain. Most people are familiar with surgical resection, radiotherapy, and chemotherapy. What is immunotherapy? What effect does immunotherapy have on kidney cancer?

It has been proven over the years that lymphocytes within solid tumors of the human body have an immune response to their tumor cells, but the cytotoxic effect of these tumor-infiltrating lymphocytes (TIL) on autologous tumors is often low because there are inhibitory mechanisms within the tumor. These TIL cells need to be stimulated and expanded in vitro to fully exert their cytotoxic effect on autologous tumors.

Normal human lymphocytes and interleukin 2 (IL-2) culture can produce effector cells called lymphokine-activated killer cells or LAK cells. A group of LAK cells and IL-2 were used to treat 57 cases of renal cancer; 36 cases of LAK cells + IL-2, and 21 cases of IL-2 alone. In the LAK cell + IL-2 group, 4 cases had complete remission (CR), 8 cases had partial remission (PR), and the effective rate was 12/36 (33%). Only 1/21 cases in the IL-2 group had CR.

Tumor infiltrating lymphocytes, or TIL cells, can also be expanded in vitro with IL-2. Animal experiments have found that this adoptive transfer of TIL has a therapeutic effect 50 to 100 times stronger than LAK cells and can destroy its lung and liver metastases. The possibility of its clinical application is still under discussion.

Through the above explanation, we know what is the immunotherapy of kidney cancer. I believe we have a certain understanding of kidney cancer. I hope this article can help you or your friends. This article is for reference only. If you have other questions, please consult our experts online.

Kidney cancer http://www..com.cn/zhongliu/sa/