What kind of people are prone to liver cancer? Introduction to the early symptoms of liver cancer

In life, we often see people who blush when drinking. Some people say that such people have a good alcohol tolerance and are easy to get along with. However, there are risks behind this good thing. The blushing reaction caused by drinking is due to genetic defects in the enzyme that metabolizes alcohol, which leads to a large accumulation of toxic acetaldehyde in the body, causing blood vessels to dilate and cause blushing reactions. People who blush when drinking may have a greater risk of liver cancer.

People who blush when drinking are more likely to develop liver cancer

According to a four-year follow-up survey, the intrinsic connection between long-term alcoholism and the risk of liver cancer is revealed. Alcoholic hepatitis B virus carriers have the highest risk of liver cancer. For one-third of the Chinese population, the "alcohol detoxification gene" has become ineffective due to mutation. Drinking is a recognized risk factor for liver cancer in addition to hepatitis B, drinking contaminated water and eating moldy food, but there has been a lack of clear identification of the risk and intrinsic connection. Studies have shown that the metabolism of alcohol in the human body is completed by acetaldehyde deoxygenase 2 (ALDH2). The function of acetaldehyde deoxygenase 2 in the human body is to oxidize acetaldehyde into acetic acid, which is not carcinogenic, and finally decomposes into carbon dioxide and water that are harmless to the human body and excreted from the body. However, when the normal gene of acetaldehyde deoxygenase 2 mutates, the enzyme will lose its activity, resulting in a more than 6-fold increase in the acetaldehyde concentration in the blood after drinking. Long-term alcoholism will accumulate acetaldehyde in the body, which may eventually lead to liver cell cancer. At the same time, drinking can also cause health damage to normal people, such as alcoholic liver disease and damage to the gastrointestinal mucosa. People should try to drink less or only drink low-alcohol drinks, such as red wine and beer; long-term drinkers should strictly control their alcohol intake to a safe dose of less than 15 grams/day.

Symptoms of liver cancer in its early stages

Liver cancer is a type of cancer. Many people suffer from liver cancer but do not know why. Some people think it is caused by excessive toxins in the body. Is this true? So what are the early symptoms of liver cancer?

1. Central necrosis of cold-heat type liver cancer can cause fever, and patients with advanced liver cancer may have irregular moderate fever.

2. Internal bleeding or rupture of the surface of the cancerous nodule in abdominal-type liver cancer can cause acute abdominal pain or intra-abdominal hemorrhage. Common rupture of liver cancer at the top of the right lobe of the liver causes pain in the right lower chest, right shoulder and back, and the pain worsens when turning the body position or breathing. Those that penetrate into the abdominal cavity may cause hemorrhagic shock.

3. Typical clinical liver cancer is characterized by asymmetric enlargement of the liver, which is hard and irregular and grows rapidly. Late-stage patients often have obvious cirrhosis, portal hypertension, ascites, jaundice, and cachexia.

4. Early or subclinical liver cancer, the tumor is small, often in hidden parts, the patient is often asymptomatic, and is only discovered accidentally during physical examination. The patient may have some non-specific manifestations, such as upper abdominal discomfort, fullness, etc.

5. Differential diagnosis of primary liver cancer: Gastrointestinal bleeding is often the cause of death from advanced liver cancer.

6. Jaundice is a major factor in the development of liver cancer. The reason is that the liver cancer tissue next to the bile duct penetrates into the bile duct to form a cancer thrombus, which grows downward and blocks the opening of the opposite hepatic duct or the common bile duct.

People who need to be screened for liver cancer are also high-risk groups for liver cancer, including chronic hepatitis B virus carriers and chronic hepatitis B patients, chronic hepatitis C patients, patients with advanced liver fibrosis and cirrhosis caused by various reasons, alcoholics, and those with a family history of liver cancer. The following high-risk groups should be screened for liver cancer in a timely manner if they have the following conditions:

1. Pain in the liver area, intermittent or persistent dull pain, dull pain or distending pain, which worsens as the disease progresses;

2. Symptoms such as loss of appetite, upper abdominal fullness after meals, indigestion, hiccups, nausea, vomiting and diarrhea;

3. Weight loss, fatigue, and general weakness;

4. Fever, which is mostly persistent low-grade fever, may also be irregular or intermittent, persistent or remittent high fever, similar to the symptoms of liver abscess, but there is no fever before the fever, and antibiotic treatment is ineffective.