The key to candidiasis is Candida albicans, which is a normal fungus that grows in the human body, mainly in the human mouth. If the number of Candida albicans in the human body does not exceed a certain value, it actually has no effect on the human body. However, if the human body's immunity decreases or the Candida albicans multiplies too much, candidiasis will occur. Candida albicans is a saprophytic fungus that is widely found in nature. It is one of the normal flora of the human body and usually lives in the human mouth, skin, mucous membranes, digestive tract, vagina and other organs. The white bacteria carrying rate in normal people can be as high as 40%; 85%-90% of the Candida isolated from the vaginal mucosa is white. The white one is the most pathogenic. Antifungal treatment 1. Nystatin can be taken orally and applied topically. For oral administration, 500,000 units each time, 4 times a day. For external use, it is in the form of suppositories, each suppository contains 250,000 units. 2. Fluconazole, also known as Dafluconazole, is usually taken orally once, 150 mg, to be effective, but it is easy to relapse after cure, so it is worth noting. 3. Itraconazole, also known as Sporanox, is generally taken at a dose of 100 mg twice a day for 10 consecutive days as a course of treatment. Topical medications for oral candidiasis 1. 2%~4% sodium bicarbonate solution (baking soda): used to clean the mouth before and after breastfeeding to eliminate residual curd or sugar that can decompose and produce acid, making the oral cavity alkaline and preventing the growth and reproduction of Candida albicans. It can also be used to clean nipples before and after breastfeeding to avoid cross-infection or repeated infection. 2. Genian violet aqueous solution: 0.5% concentration is suitable for oral mucosa, apply it 3 times a day to treat thrush and angular cheilitis in infants and young children. 3. Chlorhexidine: Apply 0.12% solution or 1% hot glue topically, rinse or gargle. It can also be combined with nystatin to form an ointment or cream. An appropriate amount of triamcinolone acetonide can also be added to treat angular cheilitis, denture stomatitis, etc. Alternating gargling with chlorhexidine solution and sodium bicarbonate solution can eliminate the gram-negative bacteria, the co-pathogens of Candida albicans. |
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