How to treat acute pancreatitis

Pancreatitis is a common clinical disease, and acute pancreatitis is also a type of pancreatitis. The onset of acute pancreatitis is relatively rapid, with obvious symptoms of abdominal pain and bloating. Early treatment is recommended for this disease. The clinical manifestations of acute pancreatitis vary in severity, and the severity of the symptoms must also be considered in treatment. So how should acute pancreatitis be treated?

1. Fasting and nasogastric tube decompression

Continue gastrointestinal decompression to prevent vomiting and aspiration. Giving whole-body motility drugs can reduce abdominal distension.

2. Replenish body fluids

To prevent and treat shock, all patients should be given intravenous fluid, electrolyte and heat supplementation to maintain circulatory stability and water-electrolyte balance. Prevent hypotension and improve microcirculation.

3. Antispasmodic and analgesic

For those with a clear diagnosis, symptomatic analgesics can be given in the early stages of the disease. However, it is advisable to give antispasmodics at the same time. Morphine is contraindicated to avoid spasm of the sphincter of Oddis.

4. Inhibit pancreatic exocrine secretion and pancreatic enzymes

Gastric tube decompression, H2 receptor blockers, anticholinesterase drugs, somatostatin, etc. are generally used for patients with more serious conditions. Trypsin inhibitors such as aprotinin and gabexate have a certain inhibitory effect on trypsin.

5. Nutritional support

Fasting in the early stage, mainly relying on total parenteral nutrition (TPN). When the abdominal pain, tenderness and intestinal obstruction symptoms are relieved, you can resume eating. Except for patients with hyperlipidemia, fat emulsion can be used as a heat source.

6. Application of antibiotics

Early antibiotic treatment. In severe pancreatitis complicated by pancreatic or peripancreatic necrosis, intravenous administration of broad-spectrum antibiotics or selective enteral administration of antibiotics can prevent bacterial infection caused by intestinal flora translocation.

7. Surgery

Pancreatic abscess, pancreatic pseudocyst, and pancreatic necrosis with infection are serious life-threatening complications of acute pancreatitis. If the diagnosis is uncertain; there is secondary pancreatic infection; there is concurrent biliary disease; or the clinical symptoms continue to worsen despite reasonable supportive treatment, surgical treatment should be performed.