How big is the follicle considered mature

Some female friends cannot conceive successfully no matter what method they use. At this time, they will become very anxious and can only resort to artificial insemination. However, sometimes artificial insemination is unsuccessful, so it is necessary to observe the condition of their own follicles and allow their follicles to develop better. Artificial insemination can only be performed after the follicles are fully developed and mature. In this way, the chance of success can be better promoted and it is easier to conceive successfully.

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When doing in vitro fertilization, women will be given ovulation-stimulating injections to promote the development of follicles. If 70%-80% of the follicles are between 14mm-22mm in diameter, it is the best time to retrieve the follicles. If only one follicle is 18mm, but the others are 10mm, the eggs cannot be retrieved. The day for egg retrieval should be determined based on the average diameter of the majority of follicles.

Mature follicles are one of the structural components of the ovary. Every month, women release a mature egg, and this egg is generally considered mature if it is larger than 20mm.

The mature follicle cavity is large and the cumulus is obvious. The endometrial cells are close to the granulosa layer of the follicle and are separated from the granulosa layer cells by a basement membrane. The endometrial cells are polygonal, with clear cytoplasm and round nuclei. Many capillaries can be seen between the cells. The exometrial cells are located in the outermost layer, mostly spindle-shaped, and have no obvious boundary with the surrounding connective tissue.

Every month, women will only release one mature egg, and this mature egg is generally considered a mature egg when it is larger than 20mm. However, there are individual differences. Some people will release the egg when the follicle grows to 15mm, while others will release the egg when it grows to 25mm. The specific individual situation can be determined by a periodic B-ultrasound examination. Generally, mature follicles will be discharged within one to two days, and the discharged follicles can generally survive for 2 days.

In order to arrange sexual intercourse time reasonably and improve pregnancy rate, it is important to predict women's ovulation period. Some women have their period once a month, while some women only have their period every 20 days, 40 days, or even 2 to 3 months. Obviously, these women did not all ovulate at the same time.

The primordial follicle is composed of a large primary oocyte and a single layer of flat follicle cells surrounding it. There are about 1 million primordial follicles in the ovarian cortex of newborns, but most of them cannot reach the mature stage. They atrophy and degenerate one after another to form atretic follicles. The development of primordial follicles into growing follicles does not require hormonal regulation.