There are some bacteria in the stomach and intestines, and there are many types of bacteria, including both beneficial bacteria and some harmful bacteria. As long as the intestinal flora is relatively balanced, people are relatively healthy. When the intestinal flora is imbalanced due to internal or external factors, it will often cause some symptoms, such as diarrhea. At this time, nutrition should be strengthened and treatment should be carried out in time. How to treat intestinal flora imbalance 1. Diet adjustment: Carbohydrate intake should be limited for fermentative diarrhea; protein intake should be limited for putrefactive diarrhea. To enhance the local defense barrier function of the intestinal mucosa and prevent bacterial translocation, fiber foods should be increased. 2. Antimicrobial drugs: Stop the original antibiotic immediately, and select appropriate antibiotics based on flora analysis and antimicrobial sensitivity tests to inhibit over-reproduction of bacteria, thereby indirectly supporting under-reproduction of bacteria in the intestine. In addition, broad-spectrum antibiotics can be used to eliminate most of the intestinal bacteria, and then the normal intestinal flora fluid can be injected to restore it. 3. Live bacteria preparations: Currently commonly used live bacterial preparations include Lactobacillus acidophilus, Lactobacillus bulgaricus, Lactobacillus lactis, Lactobacillus sporogenes, Lactobacillus bifurcate, Streptococcus faecalis, Escherichia coli, Faecalibacterium and Bacillus subtilis. Among them, the bifurcation lactobacillus preparation has the best effect. Bacillus subtilis preparations also have good therapeutic effects. The mechanism of their efficacy may be that the bacteria are aerobic and can absorb oxygen, reduce the redox potential of the intestinal cavity, support the growth of anaerobic bacteria (Bacteroides and Lactobacillus), and thus indirectly support the normal bacterial flora. Normal human stool suspension can also be used to make a compound live bacteria preparation to treat pseudomembranous enterocolitis caused by staphylococci, with good results. Lactase, made from lactic streptococci, is widely used in clinical practice and has good effects. It is also an effective method to adjust the imbalance of intestinal flora by making preparations with drug-resistant strains that have insufficient reproduction in the normal intestinal flora to facilitate the determination of the value. The latest biological product, Lizhu Changle (Huichunsheng Capsules), is a live bifidobacterium preparation (bifidobiogne). According to a study conducted by Yao Yi, this preparation has barrier effects, control of endomycinemia, nutritional effects, anti-tumor effects, immune enhancement effects, anti-aging effects, etc. 4. Bacteria promoter: Oral flora promoters can also achieve the purpose of supporting normal flora. For example, lactose is used to support Enterobacteriaceae, folic acid is used to support Enterococci, and mycobacterial factor is often used in children to promote the growth of mycobacterium. The application of galactoside-acid will form lactic acid or acetic acid after being decomposed by bacteria, which will lower the pH value, inhibit other bacteria, and support the growth of lactobacillus. 5. Drug-resistant enterococci preparations: Meguro et al. in Japan used the thickening subculture method to obtain the BIO-4R strain of Enterococcus aureus that is resistant to streptomycin, erythromycin, tetracycline, and ampicillin. Animal and human tests have shown that this bacterium is resistant to multiple antibiotics, so it can prevent the abnormal reproduction of other bacteria, overcome dysbiosis, improve abnormal stool, and is more effective than previous treatments with antibiotics alone. It can also prevent the transfer of resistance factors of fecal streptococcus BIO-4R strain to Escherichia coli K-12 strain. |
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