When it comes to papillary thyroid cancer, I believe everyone is familiar with it. It is a malignant tumor that is extremely harmful to people's health. Patients with papillary thyroid cancer must go to a regular hospital for early treatment after diagnosis to avoid delaying the disease and causing more serious consequences. Below I will introduce to you some factors related to the prognosis of papillary thyroid cancer. 1. Pathological type The prognosis of different types of thyroid cancer varies greatly. If the treatment is reasonable and timely, the survival period is almost the same as that of normal people. However, the prognosis of highly malignant undifferentiated cancer is extremely poor, and death often occurs within half a year. 2. The extent of the lesion The degree of development of the lesion, such as whether the tumor is confined to the glandular lobe, whether there is invasion of large blood vessels, whether there is lymph node metastasis, and extrathyroidal invasion, will mean a high recurrence and mortality rate, while the mortality rate of patients with occult cancer is extremely low, and their recurrence and mortality rates are relatively low; cancers with multiple nodules are more likely to recur than cancers with a single nodule, and patients can survive with the tumor for a long time, and their life expectancy after surgery can be almost the same as that of normal people; the survival rate of patients with lymph node metastasis can be reduced by 7% to 19% compared with those without lymph node metastasis. 3. Age There are also obvious differences in their prognosis, and women over 50 years old have a worse prognosis. (1) AMES multifactorial system risk group classification: Blake Cady used the multivariate regression method to analyze the various factors that affect the efficacy of papillary adenocarcinoma and proved that four factors are very important in predicting mortality, namely the patient's age and distant metastasis, which can divide patients into various risk groups with different prognoses. ① Low-risk group: young patients without distant metastasis; males under 40 years old and females under 50 years old; all elderly patients with the following conditions: intraglandular papillary adenocarcinoma or follicular adenocarcinoma with microvascular invasion or primary cancer with a diameter of less than 5 cm and no distant metastasis. ② High-risk group: all patients with distant metastasis; all young patients with follicular adenocarcinoma involving large blood vessels; all elderly patients with the following conditions: extraglandular papillary adenocarcinoma or follicular adenocarcinoma involving large blood vessels or primary cancer with a diameter of 5 cm or greater, regardless of the extent of the lesion. (2) AGES evaluation model: The Mayo Clinic in the United States followed up 860 cases of papillary thyroid carcinoma for an average of 16.5 years. After extensive analysis of various factors that may affect prognosis, it was found that four factors have a significant impact on prognosis: age. The Mayo Clinic therefore proposed the AGES evaluation model to assess the prognosis of patients with papillary thyroid carcinoma. It can be seen that the prognosis of thyroid cancer with different pathological types and different degrees of lesions varies greatly. In addition, the prognosis of thyroid cancer is also related to the age of the patient. The older the patient, the worse the prognosis. Therefore, after the diagnosis of thyroid cancer, patients must clearly classify and receive treatment as soon as possible, which is more conducive to the patient's recovery. |
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