The five-year survival rate of mid-stage laryngeal cancer can reach 60%, and the specific survival period cannot be accurately assessed. For example, the survival time of stage IV laryngeal cancer is relatively short. Therefore, if there is an abnormality in the throat, you should seek medical attention in time, diagnose laryngeal cancer, and treat it as soon as possible to achieve better results and strive for a longer survival period. Survival can be prolonged by: 1. Surgical treatment: In histology and embryology, the left and right sides of the larynx develop independently, and the supraglottis, glottis and subglottis come from different primordia; the left and right lymphatic drainage is not connected to each other, and the supraglottis, glottis and subglottis lymphatic drainage are independent, which provides a basis for surgical treatment of laryngeal cancer, especially partial resection. Different surgical procedures can be used according to the different locations of the cancer. (1) Laryngeal carcinoma in situ or mild invasive lesions are suitable for laryngeal laser surgery and plasma surgery. They have the advantages of minimally invasive, less bleeding, low tumor spread rate, and good preservation of voice function. They are mainly suitable for early cases. (2) Partial laryngectomy includes laryngeal dehiscence and vocal cord resection; frontal partial laryngectomy; vertical hemilaryngectomy; and some corresponding modified procedures are selected according to the extent of glottic cancer invasion. (3) Supraglottic laryngectomy is suitable for supraglottic cancer. (4) Total laryngectomy is suitable for advanced laryngeal cancer. 2. Radiotherapy: Cobalt-60 and linear accelerator are the main means of radiotherapy at present. For early laryngeal cancer, the cure rate and 5-year survival rate of radiotherapy are equivalent to those of surgical treatment. The disadvantage is that the treatment cycle is long and symptoms such as loss of taste, smell and dry mouth may occur. 3. Combined therapy of surgery and radiotherapy: refers to surgery plus preoperative or postoperative radiotherapy, which can increase the 5-year survival rate of surgical treatment by 10% to 20%. 4. Chemotherapy: It is divided into induction chemotherapy, adjuvant chemotherapy, palliative chemotherapy, etc. according to its effect. Induction chemotherapy is to give drugs before surgery or radiotherapy, when the tumor has rich blood supply, which is conducive to the effect of drugs. Adjuvant chemotherapy refers to chemotherapy added after surgery or radiotherapy to kill possible residual tumor cells. Palliative chemotherapy refers to the use of palliative treatment for patients with recurrence or systemic metastasis who cannot undergo surgery. Although the survival period of mid-stage laryngeal cancer is not consistent for individuals, it can be prolonged through the above treatment methods. |
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