Under what circumstances should genetic testing be performed for breast cancer?

Under what circumstances is genetic testing for breast cancer performed?

Breast cancer patients generally undergo genetic testing in the early stages of the disease, when the correct treatment drugs are selected, and in the late stages of the disease.

1. Early stage of the disease: For patients with early breast cancer, there is no lymph node metastasis and the tumor is relatively small. At this time, genetic testing is needed to assess the risk of future recurrence and metastasis, and decide whether to perform postoperative adjuvant chemotherapy based on the score of genetic testing.

2. Correctly select therapeutic drugs: For breast cancer patients, due to differences in individual genetic genes, different patients will react differently to foreign substances. Some patients may experience drug allergies, swelling, and rashes when using normal doses of drugs. Based on the results of genetic testing, a specific treatment plan can be formulated to scientifically guide the use of drugs and avoid toxic side effects of drugs.

3. Advanced disease: For patients with advanced breast cancer, TMB expression and BRCA gene mutation can be tested. If the TMB mutation load is relatively high, combined immunotherapy can be performed on the basis of chemotherapy, providing clinicians with more treatment methods.

In addition to the above situations, there may be other situations, such as predicting the risk of breast cancer in the next generation. It is recommended to go to the hospital in time, complete the examination, clarify the cause, and carry out targeted treatment or treatment under the guidance of a doctor.