What are the specific symptoms of severe hepatitis

Hepatitis is a type of disease that causes serious damage to the liver. If the patient's hepatitis develops to a serious level and obvious symptoms appear, and the patient has not been able to effectively control and treat it, it may further develop into terrible diseases such as cirrhosis and liver cancer. It must not be underestimated. Let's take a look at the specific symptoms of severe hepatitis.

1. Acute severe hepatitis

The patient suffers from acute icteric hepatitis with onset of pain, extreme fatigue and severe gastrointestinal symptoms within 2 weeks, rapid onset of grade II or above hepatic encephalopathy, prothrombin activity less than 40%, and exclusion of other causes. The boundaries of liver dullness progressively narrowed and jaundice deepened rapidly.

2. Subacute severe hepatitis

The patient presents with acute icteric hepatitis, with extreme fatigue and severe gastrointestinal symptoms within 15 days to 24 weeks, prothrombin activity less than 40%, and other causes excluded. Jaundice increases rapidly, and serum bilirubin increases by >17 μmol/L or >10 times the normal value per day. Those who first develop grade II hepatic encephalopathy are called encephalopathy type (including cerebral edema, brain herniation, etc.); those who first develop ascites and its related symptoms (including pleural effusion, etc.) are called ascites type.

3. Chronic severe hepatitis

The clinical manifestations at the onset are the same as those of subacute severe hepatitis, which worsen as the disease progresses and reach the standard of severe hepatitis (prothrombin activity <40> 10 times the normal value). The underlying lesions may include: ① chronic hepatitis or cirrhosis. ②Chronic HBsAg carriers. ③ Although there is no history of liver disease or HBsAg carrier history, there are signs of chronic liver disease (such as liver palms, spider nevi, etc.), ultrasound changes (splenomegaly) and changes in protein metabolism (such as increased globulin, decreased or inverted A/G ratio). ④ Liver puncture supports the presence of chronic hepatitis. ⑤ When chronic hepatitis B or hepatitis C or chronic HBsAg carriers have overlapping infection with hepatitis A, E or other hepatitis viruses, a specific analysis should be conducted to exclude acute or subacute severe hepatitis caused by hepatitis A, E and other hepatitis viruses.