What are the symptoms of vitamin D toxicity?

Many people have not heard of vitamin D poisoning, but only know that vitamin D can treat rickets. Sometimes rickets is misdiagnosed and excessive intake of vitamin D can lead to vitamin D poisoning. This requires everyone to pay more attention.

symptom:

VitD poisoning lacks specificity and can easily be mistaken for an early symptom of rickets, leading to the administration of more VitD. Once symptoms become apparent, it can be easily misdiagnosed as other diseases.

Clinical classification:

In the early stages, children may experience poor appetite, anorexia, nausea, fatigue, lack of energy, irritability, low fever, vomiting, constipation and weight loss. The children suffer from epidermal desquamation and hair loss. In severe cases, convulsions, high blood pressure, arrhythmia may occur, accompanied by dry mouth, frequent urination, and nocturia. Severe cases affect the cardiovascular system and may cause abnormal electrocardiogram, decreased muscle tone, movement disorders, renal failure, and even depression, coma, and convulsions. The urine has a low and fixed specific gravity, positive urine protein, increased cell count, and may also have casts. In severe cases, death may occur due to hypercalcemia and renal failure.

Clinical manifestations at different stages:

1. Early stage: The earliest symptoms in children are loss of appetite, even anorexia, irritability, crying, lack of energy, and often low fever. There may also be excessive sweating, nausea, vomiting, diarrhea or constipation, and gradual onset of thirst, frequent urination, frequent urination at night, and occasionally dehydration and acidosis. Older children often complain of headaches. Blood pressure may rise or fall, systolic murmurs may be heard in the heart, the ST segment of the electrocardiogram may be elevated, and sometimes there may be mild anemia.

2. Mid-to-late stage or chronic stage: In the late stage, symptoms such as high fever, thirst, polydipsia, polyuria, oliguria, dehydration, drowsiness, apathy, hypotonia, coma, and convulsions may appear. Long-term chronic poisoning in children can cause corresponding calcification of bones, kidneys, blood vessels, and skin. If not treated in time, kidney damage and even renal function decline may occur, seriously affecting the growth and development of children.