What does lgm positive mean

I believe that many patients do not know what symptoms the LGM positive condition manifests, because this is a relatively rare disease. It refers to the changes in Toxoplasma antibodies. If we have a positive LGM, it may be because of abnormalities in Toxoplasma antibodies. At this time, we should get vaccinated to improve our body's resistance. Moreover, the main patient population for this disease is pregnant women. I hope pregnant women can pay good attention to their bodies.

First of all, we need to understand the meaning of several test items.

Toxoplasma gondii IgM antibody (TOX-IgM)

Toxoplasma gondii IgG antibody (TOX-IgG)

Rubella virus IgM antibody (RV-IgM)

Rubella virus IgG antibody (RV-IgG)

Cytomegalovirus IgM antibody (CMV-IgM)

Cytomegalovirus IgG antibody (CMV-IgG)

Herpes simplex virus IgM antibody (HSV-Ⅰ-IgM)

Herpes simplex virus Ⅰ IgG antibody (HSV-Ⅰ-IgG)

Herpes simplex virus II IgM antibody (HSV-II-IgM)

Herpes simplex virus II IgG antibody (HSV-II-IgG)

Clinical significance of negative/positive

1. Antibody IgG

(1) Antibody IgG negative: not infected with this type of virus. Or have been infected but have not produced antibodies. This means that the pregnant woman may not have been infected with this pathogen and lacks immunity to it. She should consider getting vaccinated and wait until she produces immune antibodies before getting pregnant.

(2) Antibody IgG positive: indicates that the pregnant woman has had this virus infection in the past. or have been vaccinated. In other words, it only means that you have been infected with the virus in the past and may have become immune to it. Women who have received some viral vaccines will test positive for IgG antibodies. For example, women who have received the rubella vaccine will test positive for rubella virus IgG antibodies. Women who have been vaccinated against hepatitis B will test positive for hepatitis B antibodies. Therefore, it is necessary to distinguish which are protective antibodies and which are non-protective antibodies.

2. Antibody IgM

(1) Antibody IgM negative: There is no active infection, but potential infection is not ruled out.

(2) Antibody IgM positive: indicates that the pregnant woman has had active infection with this virus recently.

IgG+《1:512

IgM- indicates a history of infection in the past and now has protective antibodies.

IgG+≥1:512

IgM+IgG+≥1:512

A 4-fold or greater increase in either of the two serum titers of IgGab may indicate a recent infection.

IgG-

MgM- has not been infected with CMV, but for such pregnant women, serological monitoring should be carried out during pregnancy to avoid primary infection during pregnancy.