What are the symptoms of malignant lymphoma?

The symptoms of malignant lymphoma are a hot topic nowadays. Cancer is terrible, and if not treated in time, it will have very serious consequences. So what are the symptoms of malignant lymphoma ? Let the experts introduce them to us below.

Lymphoma is one of the most common malignant cancers. The initial symptoms of many patients are not very obvious. What patients and their families are more concerned about is the cure rate of lymphoma. Lymphoma is a group of malignant tumors originating from lymph nodes or other lymphatic tissues. It can be divided into two categories: Hodgkin's disease (abbreviated as HD) and non-Hodgkin's lymphoma (abbreviated as NHL). Histologically, tumor proliferation of lymphocytes and (or) tissue cells can be seen. Clinically, painless lymphadenopathy is the most typical, and the liver and spleen are often enlarged. In the late stage, there is cachexia, fever and anemia.

The cell morphology of lymphoma is extremely complex. In the new classification of lymphoma by WHO in 2008, there are 80 subtypes. Due to the different locations and ranges of lesions, the clinical manifestations are very inconsistent. The primary site can be in the lymph nodes or in extranodal lymphoid tissues, such as tonsils, nasopharynx, gastrointestinal tract, spleen, bones or skin. Primary sites in nodal lymphoid tissues are more common in NHL.

Don't be afraid if you are diagnosed with lymphoma. A large number of clinical trials have confirmed that 50%-60% of early-stage patients can be cured by immunochemotherapy, and the cure rate for late-stage patients is 30%-40%. The key to whether the disease can be cured is whether the first treatment is successful. Rituximab-based immunochemotherapy, namely the R-CHOP regimen, is a comprehensive treatment based on chemotherapy. It is currently recognized as the first-line treatment for some subtypes of malignant lymphoma and can significantly improve the long-term survival of patients.

For example, for the most common diffuse large B-cell lymphoma, 80% of patients can achieve a therapeutic response through 6 to 8 courses of R-CHOP chemotherapy. Among early-stage patients, patients under 60 years old have a cure rate of nearly 70%. Even if they are over 60 years old, early-stage patients have a cure rate of nearly 50%.

Early detection of malignant lymphoma symptoms can greatly increase the cure rate!

Clinically, due to the increase in new drugs and the continuous accumulation of comprehensive treatment experience, both short-term efficacy and long-term survival have made considerable progress, and malignant lymphoma has become a curable disease to some extent. Of course, some malignant lymphomas are more hidden and difficult to detect. If symptoms can be detected early and timely treatment is sought, the cure rate will be greatly improved.

Malignant lymphoma is a type of malignant tumor. The symptoms of lymphoma often occur in young and middle-aged people, which has a great impact on the labor force and has attracted special attention from the medical community. Malignant lymphoma is a primary lymphatic system tumor that originates from the malignant transformation of lymphocytes or tissue cells. At present, according to the international unified standards, it is divided into two categories: non-Hodgkin's lymphoma (abbreviated as NHL) and Hodgkin's lymphoma (abbreviated as HD).

What are the other symptoms of lymphoma? The malignant transformation of lymphatic tissue usually first invades the superficial or mediastinal, retroperitoneal, and mesenteric lymph nodes, and can also invade the lymph nodes in these parts at the same time. A small number of patients may have primary lymphatic organs outside the lymph nodes. Most patients show painless cervical lymphadenopathy in the early stage, and other parts such as submandibular and axillary lymph nodes will be discovered one after another later. Lymph nodes can range from soybean to jujube size, with medium hardness, uniform and plump. In the late stage of the disease, the lymph nodes will grow to a large size and fuse into lumps. The mediastinum is also one of the common sites of malignant lymphoma. Most patients often have no obvious symptoms in the early stage of the disease. Chest X-ray examination will reveal lobed shadows in the middle and anterior mediastinum. In some cases, hepatosplenomegaly may be the first symptom.

In addition to the local manifestations of these lesions, the symptoms of malignant lymphoma also include systemic manifestations caused by the tumor. Some patients have systemic symptoms such as fever, rash, night sweats and weight loss as the earliest clinical manifestations. Some patients have long-term irregular fever for unknown reasons, and then gradually develop superficial lymphadenopathy, which is diagnosed only after examination. There are also a few patients with more hidden lesions, but there are often periodic low-grade fever, persistent fever, sweating, weight loss and other symptoms that may indicate the progression of the disease. In addition, the nervous system, skin, bone marrow, etc. may also be affected.

Some malignant lymphoma symptoms are relatively hidden and difficult to detect. If symptoms can be detected early and timely treatment is sought, the cure rate will be greatly improved. Some early symptoms of lymphoma are particularly worthy of attention:

(i) Progressive lymphadenopathy without clear cause, especially when the location, hardness, and mobility of the lymph nodes conform to the characteristics of malignant lymphoma mentioned above.

(2) "Lymph node tuberculosis" has not responded to regular anti-tuberculosis treatment, and "chronic lymphadenitis" has not responded to general anti-inflammatory treatment.

(III) Lymphadenopathy and fever sometimes improve after treatment, but often recur and the overall trend is progressive.

(iv) Unexplained long-term low-grade fever or periodic fever should be considered as a possible malignant lymphoma, especially when accompanied by itchy skin, sweating, weight loss, and the discovery of superficial lymph node enlargement.

The above is the explanation given by experts on the symptoms of lymphoma, and I hope it can help you answer your questions. Experts remind everyone that if you suffer from any disease in your daily life, you must not delay treatment, as this is very dangerous, as some diseases will worsen or cause other diseases.

For more information, please visit the lymphoma special topic at http://www..com.cn/zhongliu/lb/ or consult an expert for free. The expert will then give a detailed answer based on the patient's specific situation.