Give you a detailed answer to the common causes of gallbladder cancer

Cancer is a very scary disease. To reduce the occurrence of cancer, we must understand the causes of various cancers. Gallbladder cancer is no exception. We need to correctly understand the causes of gallbladder cancer in order to effectively prevent the occurrence of this disease. What are the common causes of gallbladder cancer ? Let's talk about the common causes of gallbladder cancer.

Common causes of gallbladder cancer include:

1. Gallbladder adenoma and adenomyomatous hyperplasia

Gallbladder adenoma is a benign tumor originating from the mucosal epithelium, but in recent years it has been found that it has a high rate of canceration. Tumors larger than 10 mm, without stalks or with a wide base are more likely to become cancerous. This disease has now been basically identified as a precancerous lesion and is receiving more and more attention. This is a common cause of gallbladder cancer.

2. Ulcerative colitis

The incidence of biliary tumors in this type of patients is 10 times that of the general population, but the exact reason is unclear. The cause of gallbladder cancer may be related to changes in bile acid metabolism.

3. Abnormal common channel of bile duct

It is also a common cause of gallbladder cancer. This situation can easily lead to the flow of membrane fluid to the biliary system. The activated membrane enzymes can damage the gallbladder epithelium and cause chronic inflammation, gradually leading to atypical hyperplasia and cancer.

4. Gallstones

Many studies believe that gallstones are an important cause of gallbladder cancer, because the proportion of gallbladder cancer with gallstones is as high as 60%-100%, and the rate of gallbladder stone patients suffering from gallbladder cancer in the future can reach 3%-14%, which is several times higher than those without stones. Moreover, the larger the stone, the higher the risk of gallbladder cancer. It is generally believed that this is related to the long-term stimulation of gallstones on the gallbladder mucosa or the concurrent chronic inflammation leading to gallbladder mucosal hyperplasia, and then atypical hyperplasia and cancer.

The above are the common causes of gallbladder cancer. I hope it will be helpful to you. These causes of gallbladder cancer are relatively common. I hope you can try to avoid them. In addition, if you have any questions about gallbladder cancer, you can consult our online experts.