In the clinical trial, all subjects had taken anticancer drugs cisplatin and taxanes, but their cancer continued to develop. First, the researchers divided the patients into two groups. The first group of patients had never responded to treatment, and the other group of patients responded to treatment 6 months before treatment, but then relapsed. All patients received injections of ET743 every three weeks for at least 2 months. The researchers found that once the drug was injected at a fixed dose, patients tolerated the drug well and experienced no serious side effects. In addition, some patients saw a reduction in tumor cells, including one patient who had never responded to treatment before. |
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