Is melanoma a familial genetic disease?

Melanoma is a common malignant skin tumor that is very harmful. It is a common skin tumor caused by excessive proliferation of abnormal melanocytes. It is highly malignant and accounts for the vast majority of deaths from skin tumors. It often occurs in the skin or mucous membranes close to the skin, and is also seen in the pia mater and choroid. Its incidence varies with different races, regions, and ethnicities. So is melanoma a familial genetic disease?

The incidence of melanoma in people with a family history is 1.7 times higher than that in people without a family history. People with a family history account for about 11% of all malignant melanoma patients. Their gender distribution is no different from that of sporadic cases, but the age of onset is about 10 years earlier than that of sporadic cases. Among the 1,495 cases of malignant melanoma reported by Gupta, 26 were multi-primary. According to statistics, the incidence of multi-primary melanoma in people with a family history is 0.4% to 14%, while in people without a family history it is 1% to 5%.

Pay more attention to whether the original moles suddenly become larger or even rupture. If this happens, you should go to the hospital for further examination. For moles located in special parts, such as the soles of the feet, palms, vulva and other parts that easily cause friction with the skin, you should go to the hospital for surgical removal to avoid the malignant transformation of the moles after frequent friction.

No tumor is necessarily hereditary. The so-called hereditary nature of melanoma refers to the history of tumor in the family. In this case, the chance of getting the tumor may be higher than that of other people. Pay more attention to whether the original moles suddenly become larger or even rupture. If this happens, you should go to the hospital for further examination. For some moles located in special parts, such as the soles of the feet, palms of the hands, vulva and other parts that are prone to friction with the skin, you should go to the hospital for surgical removal to avoid the malignant transformation of the moles after frequent friction.