What diseases can be complicated by bile duct cancer

What diseases can be complicated by bile duct cancer? Some friends are unfortunately diagnosed with bile duct cancer, and they don’t know whether bile duct cancer will cause other diseases. Many diseases occur in conjunction with each other, and bile duct cancer is no exception. There are indeed some complications. Let’s take a look at what diseases can be complicated by bile duct cancer?

1. Stress ulcer bleeding: a serious complication after surgery for patients with severe obstructive jaundice. Its pathogenesis is not yet fully understood, but it is generally believed that hyperbilirubinemia and hypercholesterolemia damage the gastric mucosal barrier and reduce gastric mucosal blood flow. At the same time, patients often have concurrent infections, sepsis, malnutrition, etc. Severe surgical trauma can lead to low perfusion of the gastric mucosa, forming mucosal ulcer bleeding, and in severe cases, perforation may occur.

2. Massive intraperitoneal bleeding: It often occurs in patients with combined liver lobectomy and portal vein injury during surgery. It is also seen in bleeding at the bile-intestinal anastomosis. Fresh blood drainage from the abdominal cavity >200ml/h indicates active bleeding in the abdominal cavity. Emergency surgery is required to stop bleeding. Prevention is mainly based on accurate suture to stop bleeding during surgery.

3. Bleeding from the bile duct or the cholecystoenteric anastomosis: If the bile duct stent duct duce bloody bile, it indicates the possibility of bleeding from the bile duct or the cholecystoenteric anastomosis. Somatostatin, hemostatic drugs, blood transfusion and other treatments can be used first. If it cannot be controlled, laparotomy should be performed decisively to stop the bleeding.

4. Acute renal failure: often secondary to severe jaundice. It is often caused by insufficient effective circulating blood volume, sympathetic nerve excitement, increased activity of the renin-angiotensin system, decreased renal prostaglandins, increased thromboxane A2 and endotoxemia. It is characterized by spontaneous oliguria or anuria, azotemia, dilutional hyponatremia and hyponatremia.

5. Liver failure: Liver failure is a common cause of death during cholangiocarcinoma surgery, and is more common in patients with poor liver reserve function. Prevention includes combining preoperative liver function assessment, correctly determining the scope of surgical resection, actively performing perioperative liver protection treatment, and avoiding the use of drugs that are severely damaging to liver and kidney function as much as possible.

The above are some of the diseases that may be complicated by bile duct cancer, for your reference.