Progrp value is high, how much is a dangerous signal of lung cancer?

In the ocean of medicine, there are always some indicators that act like lighthouses to guide us. Today, we are going to discuss such a mysterious and important indicator - ProGRP, a "weather vane" closely related to lung cancer. So, how high is ProGRP to be considered lung cancer? Let's uncover this mystery together.

ProGRP (progastrin-releasing peptide) is a cell-type lung cancer tumor marker, mainly used for the diagnosis and differentiation of small cell lung cancer and non-small cell lung cancer. As for how high ProGRP is considered lung cancer, it can be understood from the following aspects:

1️⃣, Normal range and critical value: Usually, the normal value of ProGRP is between 0-46pg/mL. When the value of ProGRP exceeds this range, especially when it is greater than 100pg/mL, we need to be highly vigilant. This value often indicates that there may be a tumor in the lungs, especially small cell lung cancer.

2️⃣, Comprehensive analysis: The increase of ProGRP alone cannot directly diagnose lung cancer. The doctor 👨‍⚕️ also needs to conduct a comprehensive analysis based on the patient's age, medical history, physical signs, and symptoms, and observe 👀 whether other tumor markers are elevated. If ProGRP is only elevated at a low level, a series of tests are required, such as blood routine tests, chest X-rays, etc., to rule out the possibility of other diseases.

3️⃣. Dynamic monitoring: Changes in ProGRP levels can also be used to monitor the treatment effect of small cell lung cancer and detect recurrence in a timely manner.

High ProGRP may also be associated with other diseases:

1. Benign diseases: gastritis, liver insufficiency, and renal insufficiency.

2. Digestive system diseases: gastric ulcer, reflux esophagitis.

3. Respiratory system diseases: chronic obstructive pulmonary disease.

4. Others: nephrotic syndrome, neuroendocrine malignancies.

The increase of ProGRP is an important warning signal, reminding us of possible health risks. However, we need to look at this indicator rationally and make a correct judgment in combination with other test results and the doctor's diagnosis. At the same time, maintaining a healthy lifestyle, regular physical examinations and screening are also important means to prevent malignant diseases such as lung cancer.