What factors can cause pancreatic cancer

What factors may cause pancreatic cancer?

The specific etiology of pancreatic malignancies has not yet been clearly clinically studied, which fully reflects the complexity of pancreatic malignancies.

All diseases or lifestyle habits that cause substantial damage to the pancreas may cause pancreatic malignancies:

1. Smoking and drinking. Alcohol can damage pancreatic parenchymal cells and cause spasms of the duodenal papilla, leading to obstruction of pancreatic excretion. Pancreatic congestion can cause dilation of the pancreatic duct, thereby increasing pancreatic damage. Smoking can cause continuous contraction of the blood vessels supplying the pancreas, causing pancreatic cells to be in a state of ischemia and hypoxia, which is not conducive to the rapid recovery of damaged pancreatic cells. It can lead to the occurrence of pancreatic malignant tumors.

2. Acute pancreatitis and repeated attacks of pancreatitis can cause serious damage not only to the pancreatic tissue, but also to the tissues and organs around the pancreas. The substantial damage to the pancreas caused by activated pancreatic enzymes is often irreversible, which is an important factor in pancreatic malignancy.

3. Patients with chronic pancreatitis are often accompanied by the formation of pancreatic duct stones. The repeated stimulation and friction of pancreatic duct stones can lead to pancreatic duct mucosal lesions and eventually lead to malignant tumors.

4. Some patients have intestinal fluid reflux into the pancreatic duct. Since enteritis is alkaline and has a certain corrosive effect, it will cause varying degrees of damage to the pancreatic duct mucosa and pancreatic parenchymal cells. Once the damaged pancreatic tissue cannot be fully restored, it may develop into a malignant tumor.