Normal range of albumin in the human body

Everyone has albumin in their body, and the normal range of albumin is between 40 and 60. However, if it is lower than 40, it means that there is a lack of albumin in our body. At this time, we must take albumin injections in time to supplement it, otherwise it is likely to cause us to not absorb nutrients, and it is also easy to have some other diseases. So what is the normal range of human albumin?

1. What is albumin?

Albumin (also known as albumin, Alb) is synthesized by liver parenchymal cells and has a half-life in plasma of about 15-19 days. It is the most abundant protein in plasma, accounting for 40%-60% of total plasma protein. Although its synthesis rate is affected by the protein content in the food, it is mainly regulated by the level in plasma[1]. It is not stored in hepatocytes, and trace amounts of albumin are present in all extracellular fluids.

Regarding the filtration of albumin in the glomerulus, it is generally believed that under normal circumstances its amount is very small, about 0.04% of the albumin in plasma. Based on this calculation, the amount of albumin excreted from the glomerular filtrate per day can reach 3.6g, which is 30-40 times the amount of protein excreted in the final urine. It can be seen that most of the albumin in the filtrate can be reabsorbed by the renal tubules.

Experiments have confirmed that albumin is absorbed in the proximal tubules, degraded into small molecular fragments by hydrolases in the lysosomes in the tubular cells, and enters the blood circulation. Albumin can be internalized and taken up by cells in different tissues, and its amino acids can be used for tissue repair.

2. Normal value of human albumin

What is the normal value of human albumin? Albumin is the most abundant protein in plasma. It is synthesized by liver parenchymal cells. The synthesis rate is mainly regulated by the level of albumin in plasma. The albumin content in the diet will also affect its synthesis rate. The purpose of testing albumin is to understand the synthetic function of the liver. So, what is the normal value of albumin in the human body?

For people of different age groups, the normal value of albumin is also different. The normal range of albumin at different stages is as follows:

1. The normal range of albumin in newborns is 28~44g/L.

2. Normal albumin range after 14 years old: 38~54g/L.

3. Normal albumin range for adults: 35~50g/L.

4. Normal albumin range after 60 years old: 34~48g/L.

Experts remind that albumin testing is very important for hepatitis B patients. Low albumin is common during cirrhosis. If the albumin level is lower than 25g/L, the patient is prone to ascites.

Reason 1 for high albumin: High albumin is mainly seen in blood concentration leading to a relative increase, such as: severe dehydration and shock, massive bleeding, severe burns, kidney disease, etc.

The second reason for high albumin: In addition, high albumin can also be affected by the protein intake in the diet, and to a certain extent can be used as an evaluation indicator of individual nutritional status. Sometimes blood concentration can lead to a relatively high protein concentration. Rapid water loss during diarrhea, vomiting, and high fever can also lead to an increase in serum albumin concentration, resulting in high albumin levels.