Will the creatinine value decrease on its own?

When the detected creatinine value is high, you should be alert to whether there is a problem with the kidneys and pay attention to whether there is edema in the body. In addition, even if the creatinine value is within the normal range, do not ignore the problem of the body, because kidney disease may not necessarily be manifested if the creatinine value is measured normally. So will the creatinine level decrease on its own when it is high?

Experts told us that the reason for low creatinine is that after the kidneys are invaded by various causes, the damaged kidney intrinsic cells first undergo phenotypic transformation, forming pathological changes, stimulating the fibroblasts in the kidney to transform into myofibroblasts, and at the same time invade and stimulate the inherent normal renal tissue, causing the same lesions, thus forming an expansion and stimulation-type spread of the kidneys from point to surface, from local to overall, and thus entering the organic damage period (i.e., renal function damage period). At this time, due to the continuous damage to the kidneys, their function of excreting waste is reduced, resulting in the accumulation of toxins such as creatinine in the body, resulting in increased creatinine and urea nitrogen in the blood, decreased creatinine in the urine, and decreased renal filtration rate. At the same time, patients will also have other physical symptoms such as high blood pressure and severe edema.

In addition, experts pointed out that the creatinine substance in the human body is mainly produced by creatine in muscle metabolism, and creatinine is excreted from the body through the kidneys. Generally speaking, since the body's muscle mass is relatively stable, the amount of creatinine produced is also constant. The level of blood creatinine mainly depends on how much creatinine is excreted by the kidneys. It is worth noting that the compensatory function of the kidneys is very strong. If both kidneys are normal, then as long as one kidney is functioning, blood creatinine can be maintained at normal levels. In other words, blood creatinine will only increase when the degree of kidney damage accounts for more than half of the entire kidney. Therefore, serum creatinine does not reflect early, mild decline in renal function. Therefore, problems discovered should be solved promptly.

Creatinine is a waste product excreted by the human body, and the kidneys are the main excretory organs. High or low creatinine may indicate kidney problems. What is the reason for the decrease in creatinine? I believe everyone has understood it after listening to the explanation of our hospital's experts. Here, experts recommend that patients and friends must diagnose and treat the disease in a timely manner. Do not be blindly careless, so as not to delay the disease, worsen the condition, and cause more serious harm to the patients. If you have any other questions, you can contact our experts for consultation.