Kidney disease generally refers to abnormal kidney function. The symptoms of abnormal kidney function are very obvious, and edema is a typical symptom. For edema caused by kidney disease, the main treatment is to treat the kidney disease so as to achieve the purpose of reducing swelling. There are many ways to eliminate edema, so how to treat kidney disease edema? 1. Diuretics can reduce swelling and promote diuresis For renal edema, the main loop diuretics include furosemide, bumetanide and torsemide. When using these drugs, be careful to prevent the occurrence of hyponatremia, hypokalemia and hypochloremia alkali poisoning. 2. Osmotic diuresis By transiently increasing the plasma colloidal osmotic pressure, water in the tissues can be reabsorbed into the blood. In addition, they are filtered through the glomeruli, causing a hyperosmotic state in the renal tubules, reducing the reabsorption of water and sodium and causing diuresis. Low molecular weight dextran or 706 generation plasma is usually given by intravenous drip every other day, followed by the addition of a loop diuretic to enhance the diuretic effect. However, it should be used with caution for patients with daily urine volume less than 400 ml, as it may induce osmotic nephropathy and lead to acute renal failure. 3. Increase plasma colloid osmotic pressure Intravenous infusion of plasma or plasma albumin can increase plasma colloid osmotic pressure, promote water reabsorption in tissues and cause diuresis. The effect will be better if diuretics are used after protein infusion. Since the injected albumin will be excreted in the urine within 24 to 48 hours, it can cause glomerular hyperfiltration and tubular hypermetabolism, resulting in damage to the glomerular visceral epithelial cells and tubular epithelial cells, and promote renal interstitial fibrosis. The indications should be strictly followed. It can be considered for use in patients with severe hypoalbuminemia, severe edema and oliguria when diuresis is necessary. |
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