Purpura appears on the skin

Purpura appears on the skin

The occurrence of purpura is not unfamiliar to many people, because the incidence rate of purpura is relatively high. Of course, there are many causes of purpura, such as genetics, allergies, thrombocytopenia and other problems, which can cause symptoms of purpura in the human body. Of course, different methods are needed to treat purpura caused by different reasons. Next, I will introduce the treatment methods of purpura in detail!

1. Hereditary hemorrhagic telangiectasia

1. Hemostasis: Compression is the main method for hemostasis of superficial bleeding. For internal bleeding, consider using carbaclot (Anloxue) to help small blood vessels contract, and posterior pituitary hormone to reduce the pressure in internal visceral blood vessels.

2. Blood transfusion: Only used for those who have lost a lot of blood, but not excessively to avoid high blood pressure that makes it difficult to stop bleeding.

3. Iron supplement: suitable for patients with chronic hemorrhagic anemia.

4. Others: Hepatic artery embolization can be used to treat hepatic arteriovenous fistula. β-blockers can improve the hyperdynamic circulation state, reduce hepatic blood flow, and reduce shunt volume.

2. Allergic purpura

1. Eliminate pathogenic factors: prevent and treat infections, remove local lesions (such as tonsillitis, etc.), expel intestinal parasites, avoid foods and drugs that may cause allergies, etc.

2. General treatment

(1) Antihistamines

Such as promethazine hydrochloride, chlorpheniramine (Chlorpheniramine), astemizole (Astemizole), deschlorohydroxyzine (Clamine), terfenadine (Mindi), etc., can also be injected intravenously with calcium gluconate.

(2) Drugs that improve vascular permeability

Vitamin C, troxerutin, etc.

3. Glucocorticoids

Glucocorticoids have the effects of inhibiting antigen-antibody reaction, reducing inflammatory exudation, and improving vascular permeability. Therefore, they are effective in reducing bleeding and alleviating symptoms. They have certain effects on joint symptoms and abdominal pain in some patients, but have no obvious effect on skin purpura and nephritis.

4. Symptomatic treatment

For patients with severe abdominal pain, atropine or scopolamine can be taken orally or injected subcutaneously; for joint pain, analgesics can be used as appropriate; for severe vomiting, antiemetics can be used; for patients with vomiting blood and bloody stools, omeprazole and other drugs can be used for treatment.

5. Immunosuppressants

If the above treatment is ineffective or the disease recurs recently, immunosuppressants such as azathioprine, cyclosporine, and cyclophosphamide may be used as appropriate.

6. Anticoagulant therapy

Suitable for patients with renal type, initially with intravenous drip of heparin sodium or low molecular weight heparin and then switch to warfarin.

3. Idiopathic thrombocytopenic purpura

The treatment should be considered comprehensively based on the patient's age, degree of thrombocytopenia, degree of bleeding and expected natural condition. Those with severe bleeding should be hospitalized for treatment. For severe, life-threatening bleeding, such as intracranial hemorrhage, glucocorticoids, intravenous immune globulin, and platelet transfusions should be given promptly as first-line treatment. Even emergency splenectomy can be used as first-line treatment. At the same time, avoid using any drugs that cause or aggravate bleeding, prohibit the use of platelet function antagonists, effectively control hypertension, and avoid trauma.

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