What are the factors that lead to colon cancer

In recent years, colorectal cancer has become one of the major diseases that endangers society and human health, and it has brought great pain and distress to humans. In order to reduce the incidence of colorectal cancer, we humans should understand the risk factors of colorectal cancer:

1) Age: As age increases, the time that various pathogenic factors stimulate the colon mucosa also increases. Most patients develop the disease after the age of 50.

2) Family history: If a person's first-degree family member, such as a parent, has had colorectal cancer, his risk of developing the disease in his lifetime is 8 times higher than that of the general population [If one of your direct family members (parents, siblings or children) develops colorectal cancer before the age of 50, or if two or more people in your paternal or maternal family have colorectal cancer, then you have a family history of colorectal cancer]. About 1/4 of new patients have a family history of colorectal cancer;

3) History of inflammatory bowel diseases: Certain bowel diseases such as Crohn's disease or ulcerative colitis may increase the risk of colorectal cancer. Their risk of colon cancer is 30 times that of ordinary people;

4) History of colorectal polyps: Most colorectal cancers develop from small precancerous lesions, which are called polyps. Among them, villous adenomatous polyps are more likely to develop into cancer, with a chance of malignant transformation of about 25%; tubular adenomatous polyps have a malignant transformation rate of 1-5%;

5) Genetic background: Familial adenomatous polyposis and hereditary non-polyposis colorectal cancer are caused by mutations in the corresponding genes. These patients not only have a significantly increased risk of developing the disease, but also develop it at a younger age.

The above are the risk factors for colorectal cancer. Expert Tips: If you have symptoms of disease, do not delay diagnosis and go to a regular hospital for treatment in time to avoid delaying the disease and causing serious consequences. If you have other questions, please consult our online experts or call for consultation.

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