What factors cause colon cancer

Colon cancer is one of the common malignant tumors. It is a common digestive tract malignant tumor that occurs in the colon and ranks third among gastrointestinal tumors. Its incidence has been on the rise recently. Its 5-year survival rate after radical resection is about 50%. Clinically, it has been found that certain factors may greatly increase the risk of disease.

1. Age of onset: Most patients develop the disease after the age of 50. People over the age of 50 must pay more attention to changes in their bodies. Annual physical examinations are particularly important.

2. History of colon disease: Certain colon diseases such as Crohn's disease or ulcerative colitis may increase the chance of colorectal cancer. Their risk of colon cancer is 30 times that of ordinary people;

3. Polyps: Most colorectal cancers develop from small precancerous lesions, which are called polyps. Among them, villous adenomatous polyps are more likely to develop into cancer, with a malignant chance of about 25%; tubular adenomatous polyps have a malignant rate of 1-5%;

4. Family history: If a person's first-degree relatives, such as parents, have had colorectal cancer, his risk of developing the disease in his lifetime is 8 times higher than that of the general population. About a quarter of new patients have a family history of colorectal cancer;

5. Genetic characteristics: Some familial tumor syndromes, such as hereditary non-polyposis colon cancer, can significantly increase the chance of developing colorectal cancer, and the onset time is younger.

It is generally believed that a high-fat diet and insufficient fiber are the main causes of the disease. Studies have shown that a diet high in saturated fatty acids can increase the concentration of bile acids and neutral sterols in the colon and change the composition of the intestinal flora. Bile acids can generate carcinogens such as 3-methylcholanthrene through bacterial action, and sterol rings can also be aromatized by bacteria to form carcinogens. Dietary fiber includes cellulose, pectin, hemicellulose, lignin, etc., which absorb water, increase the amount of stool, dilute the concentration of intestinal residues, shorten the time it takes for stool to pass through the large intestine, and reduce the time carcinogens come into contact with the intestinal mucosa. If dietary fiber is insufficient, it is already one of the causes of colon cancer.

The above is an introduction to the factors that induce colon cancer. I believe everyone has a certain understanding of it. Experts suggest: If your health has symptoms of disease, you can choose the appropriate treatment according to your symptoms. Do not delay diagnosis. You should go to a regular hospital for treatment in time to avoid delaying the disease. If you have other questions, please consult our online experts or call for consultation. Believe in miracles and wish you health, happiness and joy!

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