Understanding the causes of colon malignancy

Colon cancer is a common malignant tumor of the colon, which often occurs between the ages of 30 and 60. The incidence of colon cancer in my country is extremely high, but the cause of malignant colon cancer is not clear.

Chronic inflammation of the colon can induce colon tumors. Among them, granulomas formed by chronic ulcerative colitis and chronic schistosomiasis are directly related to the occurrence of colorectal tumors. The longer the course of the disease, the higher the possibility of colorectal tumors. For patients with ulcerative colitis for more than 20 years, colorectal tumors are a common malignant tumor of the colon, which is prone to occur between the ages of 30 and 60. In my country, the incidence of colon tumors is high and is constantly increasing every year. Although the causes of intestinal tumors are not very clear so far, most medical circles believe that they are related to the following factors. The incidence of intestinal tumors is about 20%-40%.

Colon adenoma tumor transformation. Although inflammatory polyps and hamartoma polyps generally do not undergo tumor transformation, the possibility of tumor transformation cannot be ruled out because hyperplastic polyps contain adenomatous components.

Diet and tumorigenic substances are one of the causes of colorectal malignancies. Epidemiological studies have shown that the occurrence of colorectal tumors is significantly related to economic conditions and dietary structure. The incidence rate is significantly higher in economically developed areas, areas and groups with a high proportion of animal fat and protein in the diet and a low fiber content. The exact mechanism of the relationship between dietary structure and the occurrence of colorectal tumors is not yet fully understood. It is generally believed that it may be related to factors such as the metabolites of animal fat, bacterial decomposition products, and the slowing of intestinal peristalsis and increased intestinal toxin absorption due to a low-fiber diet.

Genetic factors: Except for patients with colorectal tumors caused by familial polyposis or malignant transformation of ulcerative colitis, about 5%-10% of other colorectal tumor patients have a clear family history of tumors, collectively referred to as hereditary non-familial polyposis colorectal tumors, also known as Lynch syndrome.

After reading the above information about the causes of colon malignancies, I hope it can help you better prevent colon tumors. If you have any other questions, you can come to our hospital for detailed consultation.

Colon cancer: http://www..com.cn/zhongliu/jca/jczl.html