What are the commonly used drugs for treating breast cancer

Breast cancer is one of the most common malignant tumors in women. The commonly used therapeutic drugs are introduced as follows:

Herceptin: It is a recombinant DNA-derived humanized monoclonal antibody. Its single-drug efficacy is similar to that of chemotherapy drugs, but it does not cause the adverse reactions of chemotherapy drugs such as hair loss, mucositis, and hematological toxicity, and patients have good tolerance.

Xeloda (capecitabine tablets): It is a new generation of oral fluoropyrimidine drugs, which can be quickly absorbed in the gastrointestinal tract in the form of original drugs and metabolized into anti-tumor active substances in the liver and tumor tissue. It has been approved in many countries for patients with advanced breast cancer who have failed taxane and anthracycline treatment.

Furui: It is a new generation aromatase inhibitor. Aromatase inhibitors are generally well tolerated. However, adverse reactions such as gastrointestinal disturbances, weakness, headache, hot flashes and musculoskeletal pain are common.

Sulai: The growth of breast cancer cells depends on the presence of estrogen. Estrogen in the circulation of postmenopausal women is mainly converted from androgens in the adrenal glands, liver, muscles and fat by aromatase in peripheral tissues. Therefore, inhibiting aromatase to prevent estrogen production is an effective selective treatment for postmenopausal hormone-dependent breast cancer. The drug can significantly reduce the level of estrogen in the blood circulation of menopausal women, but has no significant effect on the biosynthesis of corticosteroids in the adrenal glands.

Paclitaxel injection: Paclitaxel has been approved by the FDA for adjuvant treatment of advanced breast cancer. It can also be used to treat patients who have failed combined chemotherapy or relapsed within 6 months of adjuvant treatment. Common adverse reactions of paclitaxel are bone marrow suppression, myalgia, arthralgia, mucositis, nausea and vomiting, as well as hair loss and peripheral nerve damage.