What are the causes of gallbladder cancer

Many patients do not know much about gallbladder cancer, but this disease does exist and will seriously affect the patient's health and life. Therefore, patients with gallbladder cancer should choose different treatment methods to achieve the best treatment effect. However, people should know the reasons and avoid the occurrence of this disease. So, what are the causes of gallbladder cancer?

(1) Gallstones

Gallstones are closely related to gallbladder cancer and are the most common risk factor. Logistic regression model analysis shows that the incidence of gallbladder cancer in patients with gallstones is 7 times higher than that in patients without gallstones. Domestic studies show that 20% to 86.6% of gallbladder cancer patients have gallstones, while foreign reports show that the rate is as high as 54.3% to 100%.

(ii) Cholecystitis

Cholecystitis often triggers cancer through the gradual proliferation of the gallbladder mucosa. Studies have shown that implanting cholesterol pills in the gallbladder of hamsters induces an inflammatory state of the gallbladder, and 68% of the hamsters develop gallbladder adenocarcinoma.

(III) Benign gallbladder tumor

Benign gallbladder tumors can be divided into epithelial tumors, stromal tumors and pseudotumors. Among them, gallbladder adenoma and adenomyosis are most closely related to gallbladder cancer and are more recognized as precancerous lesions of gallbladder cancer.

(iv) Cholecystectomy, congenital bile duct dilatation, and abnormal pancreaticobiliary junction.

Both are closely related to the occurrence of gallbladder cancer. Studies have shown that the incidence of gallbladder cancer is about 25% in patients with abnormal pancreaticobiliary duct confluence, and 1.9% in patients with normal confluence.

(V) Others

It has been reported that chronic inflammatory diseases of the intestine, chronic typhoid infection of the gallbladder, Mirizzi syndrome, etc. are associated with the occurrence of gallbladder cancer.

Experts remind: Many people will suffer from gallbladder cancer, which seriously affects people's normal life. However, in order to reduce the incidence of this disease, people need to understand this disease. Few people in life really understand this disease. I hope that people can understand it as soon as possible through the above introduction.