What are the symptoms of advanced liver metastasis of gallbladder cancer

What are the symptoms of gallbladder cancer liver metastasis in the late stage? Gallbladder cancer is a malignant tumor of the gallbladder, so it is easy to metastasize, and the treatment after metastasis is more difficult, so we must detect and treat it early. Below, the author will introduce to you what are the symptoms of gallbladder cancer liver metastasis in the late stage? Let's take a look at the following introduction.

Gallbladder cancer is prone to liver metastasis, which is related to its lymphatic and venous return characteristics. Direct invasion and lymphatic metastasis are the main causes of gallbladder cancer liver metastasis, and it can also metastasize to the liver through the bile duct and veins. There are two main manifestations of late-stage gallbladder cancer liver metastasis. About half of the patients have abdominal pain, distension or discomfort in the right upper abdomen, weight loss, loss of appetite and other symptoms. These symptoms are often regarded as early warning symptoms of bile duct cancer. At the beginning of abdominal pain, there are symptoms similar to cholelithiasis and cholecystitis. The main symptoms of gallbladder cancer liver metastasis are:

1. Abdominal pain: About half of the patients have symptoms such as right upper abdominal pain, distension or discomfort, weight loss, and loss of appetite. These symptoms are often regarded as early warning symptoms for the treatment of bile duct cancer.

2. Jaundice: Patients with bile duct cancer lack typical symptoms in the early stage. Most patients seek medical treatment due to jaundice. Jaundice is the earliest and most important symptom of bile duct cancer. About 90%-98% of bile duct cancer patients have varying degrees of skin and sclera yellowing. Gallbladder cancer treatment

3. Skin itching: It may occur before or after the onset of jaundice, and may be accompanied by other symptoms such as tachycardia, bleeding tendency, mental depression, fatigue, steatorrhea, abdominal distension, etc. Skin itching is caused by increased bilirubin content in the blood, which stimulates the peripheral nerves of the skin.

4. Other symptoms: There may also be nausea, vomiting, weight loss, dark yellow urine, like soy sauce or strong tea, light yellow or even clay-colored stools, etc. When the tumor ruptures in the late stage, bile duct bleeding may occur, with black stools and positive fecal occult blood test, and even anemia may occur. When there is liver metastasis, there may be liver enlargement, cirrhosis and other symptoms.