What are the symptoms of gallbladder cancer metastasis

What are the symptoms of gallbladder cancer metastasis? Generally speaking, gallbladder cancer metastasis usually occurs in the late stage of the tumor, so it will seriously affect the patient's survival. There are three main ways of metastasis of gallbladder cancer in the late stage: lymph metastasis, blood type metastasis and liver metastasis. After clinical observation, gallbladder cancer metastasis will have the following symptoms.

Early metastasis of extrahepatic bile duct cancer is relatively rare. Gallbladder cancer liver metastasis mainly spreads directly by infiltrating upward and downward along the bile duct wall. For example, upper hepatic duct cancer can directly invade the liver, which is more common than middle and lower cancer. The most common metastasis is to the hilar lymph nodes, but it can also spread to lymph nodes in other parts of the abdominal cavity. Blood metastasis of gallbladder cancer is generally rare, except in patients with advanced gallbladder cancer. Among bile duct cancers of various parts, liver metastasis is the most common, especially high-positioned bile duct cancer. Cancerous tissue is prone to invade the portal vein, forming cancerous blood clots, which can lead to liver metastasis of gallbladder cancer. It can also metastasize to adjacent tissues such as the pancreas and gallbladder.

What are the symptoms of gallbladder cancer metastasis?

1. Jaundice: Due to the spread of cancer, about 1/3 to 1/2 of patients will develop jaundice. Jaundice is the first symptom in a few patients, and most jaundice occurs after pain. Jaundice is persistent and progressively worsens. A few patients show intermittent jaundice. Jaundice often appears in the late stage of the disease, accounting for 36.5%, mostly due to cancer tissue invading the bile duct and causing malignant obstruction. It is also accompanied by weight loss, fatigue, and even cachexia, yellowing of the skin and mucous membranes, and difficult-to-treat skin itching.

2. Right upper abdominal mass: When the disease develops to the late stage, a mass appears in the right upper abdomen or upper abdomen, accounting for 54.5%. One is that the tumor grows rapidly, blocking the bile duct and causing the gallbladder to swell; the other is that it invades the duodenum and causes obstruction symptoms; in addition, if it invades the liver, stomach, pancreas, etc., masses may also appear in the corresponding parts.

3. Right upper abdominal mass: A relatively smooth and enlarged gallbladder can be felt in the right upper abdomen. When there is no adhesion to the surrounding tissue, it is highly mobile. When there is adhesion to the surrounding tissue, several masses can be felt, and sometimes an enlarged liver or a mass of duodenal obstruction can be felt. In nearly half of the cases, a mass can be felt in the gallbladder area of ​​the right upper abdomen at the time of initial diagnosis. Some parts are hard and have a nodular feel. This mass is the gallbladder. Occasionally, due to obstruction of the cystic duct, the gallbladder may have water accumulation or abscess formation, and tenderness and rebound pain in the gallbladder area may occur. Its signs are very similar to those of acute cholecystitis or obstructive cholangitis.

4. Signs caused by metastasis: In some cases, metastatic lymph nodes can be felt above the clavicle, and metastatic masses may also appear in the breast, etc. In advanced cases, there may be gastrointestinal bleeding, ascites, and liver failure due to portal vein compression.

What are the symptoms of gallbladder cancer metastasis? Is everyone clear through the editor's introduction? If gallbladder cancer metastasis occurs, there is no need to be discouraged and actively seek treatment. Maintain a calm mind and accept scientific and reasonable treatment, and the patient's life can be effectively extended.