Are ovarian tumors also caused by genetic factors?

Many women with ovarian cysts have a large part of the cause related to genetics, and coupled with an unhealthy lifestyle, which leads to malignant tumors in the ovaries. Therefore, the occurrence of ovarian cysts is closely related to the hospital. Let's take a closer look:

Some people advocate that prophylactic oophorectomy be performed on women with children whose estimated hereditary risk of ovarian cancer is as high as 50%, but there is still a possibility of extraovarian serous papillary carcinoma arising from the pelvic intestinal epithelium after surgery.

The high risk of ovarian cancer is determined based on pedigree analysis. If a woman has a first-degree relative with hereditary ovarian cancer or other related cancers (such as breast cancer in hereditary breast-ovarian cancer syndrome), the risk of her offspring having an abnormal genotype is 50.

Genetic predisposition is an important factor in the development of a small number of epithelial ovarian cancers, and people have paid attention to the role of genetic factors in the etiology of ovarian tumors.

An estimated 10 to 15% of ovarian malignancies occur in familial clusters, of which only 5 conform to a dominant genetic transmission pattern.

The common types of hereditary ovarian malignancies are: ovarian cancer associated with breast-ovarian cancer syndrome, hereditary nonpolyposis colorectal cancer syndrome (Iynch syndrome) type II, and hereditary ovarian cancer syndrome in specific locations.

The onset age of ovarian cancer in these three types of family members who are susceptible to ovarian cancer is earlier than that in the general population, with the average age at diagnosis being 49, 35 and 52 years old, respectively; the histological type of their hereditary ovarian cancer is similar to that of ordinary ovarian cancer, with moderately and highly differentiated serous papillary cystadenomas being the most common.

Less common are ovarian granulosa-thecoma cell tumors in hereditary gastrointestinal polyposis with mucocutaneous pigmentation (Peutz-Jeghers syndrome) and ovarian fibromas and cysts in multiple nevoid basal cell carcinoma syndrome.

Hereditary ovarian germ cell tumors are rare compared with ovarian epithelial tumors, but a relatively high incidence of germ cell tumors has been found in patients with hereditary gonadal dysgenesis.

Through understanding, we know some knowledge about the inheritance of ovarian cysts. Ovarian cysts are related to genetics, so when there are women with ovarian cysts in the family, we must be more vigilant about the occurrence of ovarian cysts and be prepared to prevent them in life.