Does hamartoma affect fertility

In recent years, hamartoma has such a high probability of occurrence, which requires us to introduce hamartoma prevention into our lives. Its occurrence is inseparable from the unreasonable daily lifestyle. Many patients are very worried about hamartoma, especially for women, whether it will affect fertility. So today we will take a look at whether hamartoma affects fertility?

Hamartoma is a substantial space-occupying lesion. This disease is an autosomal dominant genetic disease (renal hamartoma is also called renal angiomyolipoma). It is a type of lipoma, composed of thick-walled blood vessels, smooth muscle and mature adipose tissue. It can occur singly or multiple times. Usually, B-ultrasound and CT examinations have a high positioning and qualitative diagnosis rate for hamartoma.

After years of detailed and in-depth research on the pathogenesis, combined with modern biomolecular theory, it has finally been concluded that the fundamental cause of the formation of various types of hamartomas is "lipoma factor". There is also a lipoma factor in the patient's body. Under normal circumstances, this lipoma factor is in an inactivated state (inactive state) and will not cause the disease under normal circumstances. However, under the influence of various internal and external environmental factors, the activity of this lipoma factor is in an active state and has a certain activity. When external factors change, coupled with changes in the internal environment of the body, the activity of the lipoma factor is further enhanced, causing abnormal proliferation of normal fat cells, resulting in the deposition of adipose tissue in the smooth muscle tissue of the capillaries, forming a protruding mass of the organs, called a hamartoma.

Renal hamartoma is a benign tumor of the renal parenchyma that can occur in both the cortex and medulla. Pathological examination shows that the tumor varies in size and can grow outside the kidney or to the collecting system. It has no complete capsule but clear boundaries. The cut surface is grayish white, grayish yellow or mixed yellow, and some bleeding foci can be seen. Microscopically, the tumor is composed of mature adipose tissue, blood vessels and smooth muscle in different proportions, and may also be mixed with fibrous tissue. It is generally believed that the main pathological basis of tumor bleeding is that the tumor contains abundant vascular tissue, and the walls of these blood vessels vary in thickness and lack elasticity. The blood vessels are tortuous and can become aneurysmal, and can rupture by slight external force.

In addition, there may be two other influencing factors:

First, the maturity of various tissues in hamartomas varies. Some contain actively growing smooth muscle and fibrous tissue, which causes the tumor to grow rapidly and increase blood supply. Some people believe that these cells have the characteristics of myoblasts and fibroblasts, have potentially invasive behaviors, and may even become malignant.

Second, the rapidly growing tumor increases in size and weight, while compressing the adjacent normal kidney tissue, causing atrophy of the normal kidney tissue or even focal ischemic necrosis. Even a slight external force can cause the interface between the tumor and the kidney to break and bleed.

Don't worry, you can be pregnant without worry. Renal hamartoma is benign, and the chance of malignant transformation is very small, accounting for about 5%. Hamartoma is one of the benign tumors of the kidney. It will not affect fertility. Guidance: It is recommended to go to a regular hospital for early diagnosis and early treatment.