Why do men develop testicular cancer

Why do men get testicular cancer? Testicular cancer is one of the most common cancers in young men, and the cause of the disease is not well known. According to statistics, the incidence rate of testicular cancer in men is 7 per 100,000, and it is increasing year by year. So, why do men get testicular cancer? Let's take a look.

Although many data suggest that the occurrence of testicular cancer may be related to testicular trauma, endocrine disorders, genetics and infection, there is a lack of sufficient evidence. So far, the most convincing is the relationship between incomplete testicular descent (cryptorchidism) and testicular tumors. A large amount of data confirms that the malignant rate of cryptorchidism, especially abdominal cryptorchidism, is much higher than that of normal descended testicles, which is 3 to 14 times the incidence of normal people.

It is currently believed that factors such as testicular germ cell abnormalities, elevated temperature, blood supply disorders, endocrine disorders, and gonadal dysgenesis may be associated with the malignant transformation of cryptorchidism. The relationship between cryptorchidism and testicular tumors has attracted the attention of scholars from various countries, who emphasize that orchiopexy before the age of 6 is an effective measure to prevent the malignant transformation of cryptorchidism, and has achieved significant results.

The incidence of cryptorchidism in China is similar to that in other countries, but the proportion of cryptorchidism tumors is significantly higher than that in other countries, which may be related to the fact that China has not yet generally performed testicular traction fixation on children with cryptorchidism before school age. Testicular cancer responds well to chemotherapy, which is generally believed to be more effective in treating seminoma, embryonal carcinoma and choriocarcinoma.

The treatment of testicular cancer is divided into surgical treatment, radiotherapy, chemotherapy and comprehensive treatment. The basic surgical method is orchiectomy and retroperitoneal lymph node dissection. Radiotherapy is extremely sensitive to seminoma, embryonal carcinoma and malignant teratoma are less sensitive to radiation, and choriocarcinoma is extremely insensitive to radiation.