What are the early symptoms of lymphoma and what are the treatments?

What are the early symptoms of lymphoma? What is the treatment method?

Malignant lymphoma is a large and heterogeneous type of cancer. Although it is more likely to occur in lymph nodes, due to the distribution characteristics of the lymphatic system, lymphoma is a systemic disease that can invade almost any tissue and organ in the body. The clinical manifestations of malignant lymphoma have certain common characteristics, but also vary greatly according to different pathological types, sites of invasion and ranges.

Malignant lymphoma may present systemic symptoms such as fever, itching, night sweats and weight loss before or at the same time as lymphadenopathy is discovered. 10% to 20% of patients may have anemia when diagnosed with malignant lymphoma. Some patients may have increased white blood cell count, thrombocytosis, and increased erythrocyte sedimentation rate. Some patients may have leukemoid reactions and a significant increase in neutrophils. The increase in lactate dehydrogenase is related to tumor load. Some patients, especially those in the advanced stage, show abnormal immune function. In B-cell NHL, varying amounts of monoclonal immunoglobulins can be detected in the serum of some patients.

What is the treatment for early stage lymphoma?

1. Radiotherapy Some types of lymphoma can be treated with radiotherapy alone in the early stages. Radiotherapy can also be used for consolidation therapy after chemotherapy and adjuvant therapy during transplantation.

2. Chemotherapy for lymphoma chemotherapy is often combined with targeted therapy drugs and biological agents. In recent years, chemotherapy regimens for lymphoma have been greatly improved, and the long-term survival of many types of lymphoma has been greatly improved.

3. Bone marrow transplantation: For patients under 60 years old, medium- and high-risk patients who can tolerate high-dose chemotherapy, autologous hematopoietic stem cell transplantation can be considered. Some young patients with relapse or bone marrow invasion can also consider allogeneic hematopoietic stem cell transplantation.