Is there anyone who has been cured of neurofibromatosis? Is it contagious?

Neurofibromatosis is a hereditary disease that is currently incurable and not contagious through contact. Treatment is mainly aimed at relieving symptoms and controlling complications, including medication, surgical intervention, and regular follow-up observation.

1 Causes of the disease

Neurofibromatosis, or NF for short, is a hereditary disease, and its main cause is related to gene mutation. It is divided into type I NF1 and type II NF2. The pathogenic gene of NF1 is located on chromosome 17, and NF2 is related to gene changes on chromosome 22. This type of disease is directly inherited from the parents' genes, or caused by gene mutations at birth, and is not caused by external environment, eating habits, or contact with other sick people, so it is not contagious.

2 Analysis of whether it can be cured

There is no cure for neurofibromatosis. However, personalized interventions based on different symptoms can effectively improve quality of life, such as:

Drug treatment: For tumor enlargement or concurrent pain, PD-1 inhibitors can be used to autonomously inhibit lesion growth and analgesics can be used to relieve symptoms, but they must be used under the guidance of a doctor.

Surgical treatment: For benign tumors with a large lesion area, surgical resection is a common choice; for example, for acoustic neuromas in NF2 patients, microsurgery can be performed depending on the location.

Physical and psychological intervention: Some patients may have tumors that affect their appearance or cause difficulty in movement, and physical rehabilitation training or psychological counseling may be used to help them restore their daily abilities.

3 How to manage and prevent worsening of the disease

Although there is no cure, the condition can be significantly reduced with professional medical intervention and active management:

Regular medical checkups: Periodic MRI or brain scans may be necessary to monitor for changes in the condition, especially in people with NF2, to monitor for deterioration of the inner ear or optic nerves.

Protect the quality of daily life: Avoid excessive fatigue and external injuries in daily life, and pay attention to reasonable diet and exercise habits to enhance the body's immunity and slow down the progression of the disease.

Genetic counseling and early intervention: Families planning to have children should consider genetic testing to understand the risk level. At the same time, medical technologies such as preimplantation genetic diagnosis (PGD) may help screen embryos that do not carry the NF gene for healthy births.

Neurofibromatosis is a non-contagious genetic disease that is currently incurable, but symptoms can be effectively alleviated through comprehensive treatments such as medication and surgery. Patients need to maintain a positive attitude and follow professional regular follow-up and control their condition in order to improve their quality of life as much as possible. Families with genetic risks are advised to consult medical experts in advance to reduce the possibility of inheritance in the next generation.