How to treat severe acute aplastic anemia?

Bleeding is the main symptom of acute severe aplastic anemia. Organ bleeding and even intracranial hemorrhage may occur, which can be life-threatening and cause infection. At the beginning, the symptoms are not obvious, but as the disease progresses step by step, it may cause bleeding throughout the body. If the patient is not treated in time, he will die within six months to a year. So everyone must pay attention to it. So, how to treat acute and severe aplastic anemia?

Aplastic anemia is anemia caused by decreased or insufficient (disordered) bone marrow hematopoietic function. Causes of aplastic anemia: related to contact with certain harmful substances and taking certain drugs, such as benzene, arsenic, iodine amines, chloramphenicol and radiation. Some organic diseases such as tuberculosis, liver and kidney diseases, leukemia, etc., can often be complicated by aplastic anemia. Symptoms of aplastic anemia: In addition to the general symptoms of anemia, patients with this type of anemia often have subcutaneous or mucosal bleeding, as well as chills and fever.

It includes etiological treatment, supportive therapy and various measures to promote the recovery of bone marrow hematopoietic function. The chronic type is generally treated with androgens as the main treatment, supplemented by other comprehensive treatments. Only after long-term and unremitting efforts can satisfactory results be achieved. In many cases, hemoglobin returns to normal, but platelets remain at a low level for a long time. There are no clinical bleeding symptoms and the patient can resume light work. The acute type has a poor prognosis, and the above treatments are often ineffective. Once the diagnosis is established, bone marrow transplantation or anti-lymphocyte globulin should be used for treatment as soon as possible. Aplastic anemia should be regarded as a medical emergency, especially severe aplastic anemia, and active treatment measures must be taken immediately. Hematopoietic stem cell transplantation and the use of immunosuppressants are two treatment methods with clear efficacy for severe aplastic anemia and should be adopted as early as possible. It is common in clinical practice that the best treatment opportunity is lost due to the hesitation of doctors and patients in adopting the above two measures, resulting in patients suffering from serious infections and endangering their lives. In addition, some patients with mild aplastic anemia may gradually develop into severe disease during the course of the disease. Therefore, follow-up observation is required for the first onset of mild aplastic anemia, and attention should be paid to removing white blood cells when blood and platelets are transfused to reduce the risk of severe rejection reactions when hematopoietic stem cell transplantation is used in the future.

Aplastic anemia can cause many complications. Many data show that chronic aplastic anemia is better treated at the beginning and will have significant results. The cure rate can be as high as 90% with a treatment course of less than half a year. Therefore, early detection and early treatment are particularly important for this disease. I wish everyone a speedy recovery!