What are the symptoms of platelet aplastic anemia?

Many patients are not very familiar with platelet aplastic anemia. In fact, this disease is very rare in our daily life. The main symptoms of this type of disease are anemia, skin infection, or internal bleeding. Once this disease occurs, you need to go to the hospital for treatment in time. So, what are the symptoms of platelet aplastic anemia?

(1) Anemia: It usually presents a progressive worsening, with obvious symptoms such as pallor, fatigue, dizziness, palpitations and shortness of breath.

(ii) Infection: Most patients have fever, with body temperature above 39°C. Some patients suffer from uncontrollable high fever from the onset of illness to death. Respiratory tract infection is the most common, followed by digestive tract, urogenital tract, skin and mucous membrane infections. The infecting bacteria are mainly Gram-negative bacilli, Staphylococcus aureus and fungi, often accompanied by sepsis.

(III) Bleeding: There are varying degrees of bleeding in the skin, mucous membranes and internal organs. The skin manifests as bleeding spots or large ecchymosis, the oral mucosa has blood blisters, and there are nose bleeding, bleeding gums, and conjunctival bleeding. Bleeding from deep organs may cause vomiting of blood, hemoptysis, blood in the stool, hematuria, vaginal bleeding, fundus bleeding and intracranial hemorrhage, the latter of which often endangers the patient's life.

Testing

(I) Routine blood test: severe reduction in all three blood cell lines, progressive decrease in hemoglobin, significant reduction in white blood cells, neutrophil count usually 0.5×10/L, platelet count usually 20×10/L, reticulocyte count 0.01, and absolute reticulocyte count 15×10/L.

(ii) Bone marrow image: decreased proliferation in multiple sites, thin puncture fluid, increased oil droplets, extremely decreased granulocyte and erythroid hematopoietic cells, no megakaryocytes, increased non-hematopoietic cells, increased small granular non-hematopoietic cells and adipocytes in the bone marrow. Through the introduction above, I believe everyone has a detailed understanding of platelet aplastic anemia. We must learn to prevent this disease in daily life. This disease also has a great impact on the patient’s internal organs. In severe cases, internal bleeding and other phenomena are prone to occur, so we must prevent this disease.