Rosacea, also known as rosacea, is a chronic inflammatory skin disease that is characterized by redness of the patient's skin and papules. There are many ways to treat rosacea. In addition to medication, patients must also maintain regular living and eating habits. 1. Internal medication (1) Vitamin B group drugs, such as vitamin B2, B6 and vitamin B complex. (2) Chloroquine 0.25 g, twice a day. After 2 weeks, reduce to 0.125 g per day. Take for 1 to 2 months, not more than 3 months. (3) Metronidazole: 0.2 g each time, 3 times a day, for 2 to 4 weeks. It is suitable for patients with papule-pustular lesions and Trichomonas found. (4) For patients with obvious papules and pustules, oral antibiotics can be used, such as tetracycline 0.25g, 2 to 4 times a day. After taking it for 4 weeks, change to 0.25g once a day for 3 to 6 months. Other antibiotics such as erythromycin and minocycline can also be used. 2. Local treatment (1) Commonly used sulfur-containing preparations, such as compound sulfur lotion, white lotion, etc. (2) Chloramphenicol tincture (chloramphenicol, salicylic acid plus 75% ethanol). (3) 10% metronidazole cream or gel, etc. 3. Physical therapy (1) Electrolysis is suitable for small areas of capillary dilation. (2) Cryosurgery is suitable for the rhinophyma stage. 4. Systemic treatment (1) Since the cause is unknown, treatment is mostly symptomatic. Try to prevent factors that aggravate the disease, adjust the endocrine system, correct gastrointestinal dysfunction, avoid smoking, coffee, spicy and irritating foods, avoid overeating, keep bowel movements smooth, avoid using alkaline soaps, alcohol, detergents, dyes, astringents, etc. that irritate the skin, and avoid exposure to sunlight. (2) Antibiotics: Use the same treatment as for acne vulgaris, or use metronidazole 0.2g, 3 times/day, take it for two weeks, then change to 2 times/day for 1 month. Because long-term use has systemic side effects and toxicity, this drug is a second-line drug and is used when other methods are ineffective. Alternatively, use tinidazole (sulfonidazole, metronidazole sulfonyl imidazole) 0.5g, 2 times/day, 2g for the first time, and 7 days as a course of treatment. (3) Retinoic acid gel (isotretinoin): It is usually used for rosacea that is not sensitive to antibiotics, such as lupus rosacea, stage III rosacea, Gram-negative rosacea, etc. 0.5 mg/(kg·d) is the standard dose for rosacea. 0.1-0.2 mg/(kg·d) or 2.5-5.0 mg/d can also be used for treatment for 6 months. It is suitable for rosacea at all stages and persistent edematous rosacea. This drug can cause teratogenesis and is contraindicated for pregnant and lactating women. |
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