The cause of constrictive pericarditis turns out to be this

As we all know, constrictive pericarditis is extremely harmful to human health. Therefore, it is particularly important to understand the cause of constrictive pericarditis and prevent it. So what are the causes of constrictive pericarditis in daily life? In fact, the occurrence of constrictive pericarditis is mainly caused by tuberculosis infection.

1. Causes

The main cause of constrictive pericarditis is tuberculosis infection. Bacteriological and histological examinations confirmed tuberculosis in 30% of the lesions. In more than 50% of cases, the causative factor cannot be identified. However, in many cases, due to long-term anti-tuberculosis drug treatment, the evidence of tuberculosis lesions has disappeared when pericardial constriction occurs.

2. Pathology

The main pathophysiological changes of constrictive pericarditis are that the constricted pericardium restricts the normal activity of the bilateral ventricles. In the early stage of the disease, the main manifestation is that the late ventricular diastole is restricted. As the disease progresses, the mid-diastole is also significantly affected. During left ventricular diastole, intraventricular pressure rises rapidly, blood return to the left and right ventricles is obstructed, and venous pressure increases, manifesting as distended neck veins, hepatomegaly, ascites, pleural effusion and generalized edema. A small number of patients may experience splenomegaly. Cardiac output is slightly lower than normal, and stroke volume is significantly reduced. During physical activity or in severe coarctation, cardiac output is maintained primarily by increasing heart rate. When annular narrowing occurs in the atrioventricular groove and the roots of large blood vessels, murmurs and signs of valvular dysfunction in the corresponding areas may occur. The disproportionate degree of ascites and peripheral edema is a major feature of this disease. The mechanisms of ascites are as follows: ① Obstructive congestion of the liver, obstruction of hepatic venous return; ② Pericardial adhesions on the diaphragmatic surface affect lymphatic return; ③ Decreased plasma albumin.