What causes colitis?

Colitis is a common disease in daily life. If it is not treated in time or the treatment method is inappropriate, it can easily lead to worsening of the disease and endanger human health. So what exactly causes colitis? Most people don't quite understand this issue. In fact, the onset of colitis is related to many factors, the most direct cause of which is infection.

1. Infection: The pathological changes and clinical manifestations of this disease are similar to those of some colon infectious diseases (such as bacillary dysentery), so some people believe that infection is the cause of this disease. Among various factors such as bacteria, fungi and viruses, current research shows that viruses are more likely.

2. Genetics: The disease has a higher incidence in blood-related families. According to medical literature statistics, about 15-30% of the direct blood relatives of patients with ulcerative colitis will develop the disease. In addition, studies on twins have shown that monozygosity is more likely to develop the disease than dizygosity, suggesting that the occurrence of this disease may be related to genetic factors.

3. Neuropsychiatric factors: Some people believe that mental factors play a certain role in the onset of the disease. Most patients have certain personality traits and have poor psychological tolerance and adaptability to major events in life. They belong to the category of psychosomatic diseases. Psychosomatic diseases emphasize that psychological factors play an important role in the occurrence or course of the disease. Some people list 7 diseases as psychosomatic diseases, namely: asthma, rheumatoid arthritis, ulcerative colitis, primary hypertension, neurodermatitis, hyperthyroidism and duodenal ulcer. There are probably many more conditions that are currently classified as psychosomatic.

4. Autoimmune reaction : Most scholars believe that this disease is an autoimmune disease. Because this disease is often complicated by autoimmune diseases (such as autoimmune hemolytic anemia), adrenal cortex hormones can relieve the condition, and anti-colonic epithelial cell antibodies can be detected in the serum of some patients, so it is believed that the occurrence of this disease may be related to autoimmune reactions. In addition, after some patients are infected with intestinal bacteria, they may have an immune response to colon epithelial cell antigens, damaging the colon mucosa, and the patient's lymphocytes have a cytotoxic effect on fetal colon epithelial cells, suggesting that the occurrence of colitis may also be related to abnormal cellular immunity.

Ulcerative colitis is not an ordinary inflammation, it is a very complicated disease. The number of patients with colon cancer caused by colitis increases gradually every year, mainly because many patients do not pay attention to it. Experts remind: Chronic colitis can easily cause multiple inflammatory complications, such as heavy blood in the stool, which can cause the patient to go into shock due to excessive blood loss. Enteritis infection can lead to intestinal stenosis and random attacks of intestinal ulcers, which can easily cause intestinal perforation. The mortality rate is as high as 41%. 5% of people with colitis eventually develop cancer, leaving lifelong regrets. We hope that patients will pay great attention to this.