What are the taboos of Ji Ke's effects and functions

In fact, the shell of the Chinese wolfberry can be used as medicine, and its medicinal efficacy and value are also relatively high. It can effectively improve the problem of indigestion, especially for solving food accumulation or loss of appetite. At the same time, it can also play a diuretic role, but we must also pay attention to some possible contraindications, such as it can constrict blood vessels and cause high blood pressure.

1. The fruit of the jellyfish shell increases coronary blood flow and renal blood flow, and reduces myocardial oxygen consumption. Intravenous injection of 0.02-0.5 mg/kg into anesthetized dogs shows a pressor effect. The large dose has a significant pressor effect. Intravenous infusion of 0.2 mg/kg per minute will increase renal blood flow by 75% and double urine volume. It has a strong effect of inducing myocardial rhythm, which is comparable to that of adrenaline and stronger than dopamine and synephrine. Synephrine contained in Citrus aurantium is an adrenaline a-receptor stimulant and also has a certain stimulating effect on cardiac B-receptors. It constricts blood vessels and increases blood pressure.

2. Diuretic effect: Intravenous injection of Zhishi injection and N-methyltyramine in dogs can significantly increase urine volume, while blood pressure and renal vascular resistance are significantly increased. Its diuretic effect may be produced by inhibiting tubular reabsorption and other effects. Other studies believe that Zhishi exerts its sodium excretion and diuretic effects by strengthening the heart, constricting renal blood vessels, and increasing filtration pressure.

3. Effect on gastrointestinal smooth muscle: Zhishi decoction showed an inhibitory effect on part of the isolated intestinal tract of mice, while it showed an inhibitory effect on the entire isolated intestinal tract of rabbits. This effect can be antagonized by acetylcholine. However, when 100% Citrus aurantium was gavaged into the stomach of dogs with gastric and intestinal atrophy, it had a stimulating effect and could increase the rhythm of gastrointestinal motility and contraction. When dogs were gavaged with 100% concentrated Zhishi liquid at 1 ml/kg, it was found that the period and phase I duration of the interdigestive period integrated electromyography of the small intestine were shortened, while the phase II duration was prolonged. This shows that Citrus aurantium can enhance the tension and phase contraction function of small intestinal smooth muscle.