The value of sunflower liver protection tablets is very wide. They can adjust the body's qi and blood, resist fibrosis, and promote changes in our fat snow conditions. They can increase the liver's detoxification ability and repair damaged liver cells. Although the efficacy and effects of these medicines are relatively good, many people with unsuitable physical conditions cannot use them indiscriminately. They need to be taken under the guidance of a doctor to be more effective, and avoid indiscriminate use that will cause burden and harm to the body. Pharmacological Action This product has a protective effect on acute and chronic liver damage in animals caused by chemical poisons such as CCl4, thioacetamide, D-galactosamine, and paracetamol. It can reduce liver cell swelling, ballooning, and necrosis, prevent fatty changes, resist fibrosis, and significantly reduce serum ALT activity (schisandrin B is the main enzyme-lowering component). Its mechanism is: 1. Protect liver and reduce enzymes : Schisandra chinensis, Bupleurum chinense, Artemisia capillaris, and Isatis indigotica root can significantly reduce the increased serum alanine aminotransferase activity caused by acute and chronic liver damage in animals induced by chemical poisons such as CCl4, thioacetamide, D-galactosamine, and paracetamol, and at the same time alleviate the liver cell damage caused by these substances. 2. Enhance liver detoxification ability : ① Induce hepatic drug enzymes: Schisandrin A, B, C, Artemisia capillaris chromone, Artemisia capillaris flavonoids, etc. can obviously induce the activity of hepatocyte microsomal cytochrome P450, significantly increase its content, promote the synthesis of hepatic drug enzymes and enhance the activity of hepatic drug enzymes. ②Inhibit enzyme activity: Artemisia capillaris chromone, 6,7-dimethoxycoumarin, Artemisia capillaris flavonoids, etc. can inhibit the activity of β-glucuronidase and reduce the decomposition of glucuronic acid. This shows that Sunflower Liver Protection Tablets can accelerate the metabolic rate of chemical poisons in the liver and reduce their liver toxicity. 3. Repair damaged liver cells : ① Promote the synthesis of glycogen and protein in the liver: Schisandrin B and other substances can significantly increase the rate at which C-phenylalanine is incorporated into liver protein, thereby promoting protein synthesis. Schisandrin B, Schisandrin A, Schisandrin A and Schisandrin B can significantly and directly promote the formation of liver glycogen. Bupleurum can promote liver protein assimilation and increase liver glycogen. ② Promote hepatocyte proliferation: Bupleurum saponin and Artemisia capillaris can promote hepatocyte DNA synthesis and inhibit the synthesis of extracellular matrix. ③ Anti-cell oxidation and aging: Schisandrin B and other ingredients can increase the activity of SOD and CAT in the liver cytoplasm, enhance the antioxidant system of liver glutathione, reduce the damage of oxygen free radicals to liver cells, inhibit liver microsomal lipid peroxidation caused by CCl4 and SO4/cysteine, reduce the generation of malondialdehyde (MDA) in the liver, and improve the survival rate of liver cells. ④ Stabilize cell membrane: Schisandrin B and indigo can maintain the stability of liver cell membrane under oxidative damage, protect the integrity of cell membrane structure and normal function. Bupleurum saponin and Artemisia capillaris can directly protect the integrity of cell membranes and stabilize organelle membranes. |
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