Hepatocyte growth hormone injection

Hepatocyte growth factor injection is actually hepatocyte growth factor for injection, which is mainly used as an auxiliary treatment for various severe viral hepatitis. Severe viral hepatitis is the most serious type of infection. Any medication must be used with caution to maximize its efficacy in order to achieve the best therapeutic effect. Therefore, we need to form a comprehensive understanding of the drug hepatocyte growth factor injection. Let's take a look at the situation of hepatocyte growth hormone injection.

The main ingredient of hepatocyte growth factor for injection is a small molecule polypeptide active substance extracted and purified from fresh suckling pig liver. Excipients: 20mg of hepatocyte growth factor for injection is mannitol and sodium hydroxide; 60mg, 80mg, and 100mg of hepatocyte growth factor for injection are dextran and sodium hydroxide. It is used for the auxiliary treatment of various severe viral hepatitis (early or middle stages of acute, subacute, and chronic severe hepatitis).

Indications

Used as an auxiliary treatment for various severe viral hepatitis (acute, subacute, early or middle stages of chronic severe hepatitis).

Dosage

Intravenous injection: 80-100 mg of this product is added to 250 ml of 10% glucose solution and slowly administered intravenously once a day. The course of treatment depends on the condition, generally 4-6 weeks. For chronic severe hepatitis, the course of treatment is 8-12 weeks.

Intramuscular injection: 40 mg of this product can also be used for intramuscular injection after dilution with 0.9% sodium chloride injection, twice a day.

Pharmacology and Toxicology

This product is a small molecule polypeptide active substance extracted and purified from fresh suckling pig liver, and has the following biological effects:

① It can significantly stimulate the DNA synthesis of new liver cells, promote the recovery of damaged liver cell mitochondria and rough endoplasmic reticulum, promote liver cell regeneration, accelerate the repair of liver tissue, and restore liver function.

② Improve the phagocytic function of Kupffer cells in the liver, prevent further damage to liver cells by toxins from the intestine, inhibit the activity of tumor necrosis factor (TNF) and Na+, K+-ATPase activity inhibitory factor, thereby promoting repair after liver necrosis. It also has the effect of lowering transaminase, serum bilirubin and shortening prothrombin time.

③It has a good protective effect on carbon tetrachloride-induced hepatocyte damage.

④ It has a significant effect on improving survival of liver failure induced by D-galactosamine.

Precautions

①The use of this product should be based on comprehensive treatment for severe hepatitis.

②Be careful of allergic reactions and use with caution if you have allergies.

③Dissolve before use. It will be a light yellow transparent liquid after dissolution. Do not use if there is precipitation or turbidity.

④ Do not use freeze-dried products when they have turned brown.

⑤ Preparations for intramuscular injection cannot be used for intravenous drip.