What are the precautions for intravenous infusion of magnesium sulfate

Magnesium sulfate can treat many diseases, such as the common pregnancy-induced hypertension, but it is also prone to some side effects, such as suppressing the patient's breathing and causing hypotension. Therefore, patients must check their blood pressure regularly after taking the medicine, and also pay attention to their breathing conditions. Let us take a detailed look at the precautions for intravenous infusion of magnesium sulfate.

First, what are the precautions for intravenous infusion of magnesium sulfate? The knee reflex must be present. Respiratory rate should be no less than 16 times/min. The urine volume should be no less than 600 ml every 24 hours, or no less than 25 ml per hour. Oliguria indicates excretion dysfunction. In case of poisoning, 10 ml of 10% calcium gluconate can be injected intravenously within three minutes. The appropriate infusion rate of magnesium sulfate is 1g/h and should not exceed 2g/h. Toxic reaction of magnesium sulfate: The first manifestation is weakening or disappearance of knee reflex. As the blood magnesium concentration increases, systemic muscle hypotonia and respiratory depression may occur. In severe cases, the heart may suddenly stop.

Second, intravenous drip of 25% solution, 20 ml of which is diluted with 5% to 10% glucose to a 1% concentration for drip. ② Inject 25% 20ml intramuscularly each time, the total amount is 20-25g per day for moderate pregnancy-induced hypertension syndrome, and up to 30g per day for eclampsia; ② To inhibit uterine contractions, place 40ml of 10% solution in 20ml of 25% glucose and slowly push it intravenously. Later, add 60ml of 25% solution to 1000ml of 5% glucose and drip it intravenously at a rate of 2.0g per hour until uterine contractions stop; ③ For external use, soak gauze with 50% solution and apply hot compress to local areas such as cervical edema. When using this product, please note that the breathing rate must be greater than 16 times/min, the urine volume must be greater than 600ml/d, and the knee reflex must be present. In case of magnesium poisoning, 10 ml of 10% calcium gluconate should be injected intravenously in time for detoxification.

What are the precautions for intravenous infusion of magnesium sulfate? During catharsis, if a large amount of solution with too high concentration is taken, a large amount of water may be absorbed from the tissue and cause dehydration; because intravenous injection is more dangerous, it should be mastered by experienced physicians, the injection should be slow, and attention should be paid to the patient's breathing and blood pressure. If poisoning occurs (such as respiratory muscle paralysis, etc.), 10% calcium gluconate injection 10ml can be used for intravenous rescue; patients with intestinal bleeding, acute abdomen, pregnant women, and menstruating women are prohibited from using this product as a catharsis; patients poisoned by central nervous system depressants (such as phenobarbital) should not use this product as a catharsis to eliminate the poison to prevent aggravation of central nervous system depression.