The ovaries of adult women produce eggs. Generally, one egg is released every month. Sometimes two eggs are released every month, which makes it easy for twins to occur. So how long does it take for ovulation to be completed? When the follicle matures and forms an egg, the egg leaves the ovary and enters the abdominal cavity. This is the process of ovulation. The ovulation process is very short. Let's understand the mechanism of ovulation. The exact mechanisms and details of ovulation are not well understood. However, before and after ovulation, the feedback regulation reaction between FSH, LH, estrogen and gonadotropin-releasing hormone secreted by the hypothalamus in the body leads to regular and drastic changes in hormone levels before ovulation, which is the inducement for ovulation and the formation of the corpus luteum after ovulation. It has been observed that three hormone peaks play an important role in the occurrence of ovulation: the first estrogen peak occurs, inducing an increase in GnRH release, thereby triggering the almost synchronous secretion peaks of LH and FSH. In the process of inducing ovulation, FSH and LH must work synergistically. Only when a certain ratio of FSH and LH work together can ovulation be effectively induced. When LH is used alone to induce ovulation, all the follicles recruited by the ovaries will rupture. When a certain ratio of FSH and LH is used to induce ovulation, only mature follicles will rupture and ovulate. The exact mechanism by which this phenomenon occurs is unclear. (1) Decreased follicle wall tension
Before ovulation, the pituitary gland secretes more LH, which can promote the secretion of progesterone. The latter prompts the ovaries to synthesize a variety of enzymes, which denature the proteoglycans that act as adhesion between the collagen fibers in the top tissue of the mature follicle, thereby reducing the tension of the follicle wall. (2) Enzyme dissolves the follicle wall It has been proven that there are proteolytic enzymes, amylase, collagenase, hyaluronidase, etc. in follicular fluid. Therefore, it is believed that ovulation is caused by the above enzymes dissolving and rupturing the follicle wall, leading to ovulation. (3) Related to prostaglandins
LH can promote the synthesis of prostaglandins by granulosa cells, and the PG content in mature follicles increases progressively as ovulation approaches. PG2α can promote the contraction of smooth muscle fibers in the interstitial tissue surrounding the follicle, causing the follicle to rupture and ovulate. |
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