Adverse reactions to ipv vaccines

Polio vaccine is the most important preventive medicine in life. It can effectively prevent the occurrence of poliomyelitis and protect people's health from damage. There are two main types of polio vaccines. Among them, the IPV vaccine is used in larger quantities and is the most commonly chosen type for injection. However, this type of vaccine has certain adverse reactions. Let’s take a look at the adverse reactions of the IPV vaccine.

The low adverse reaction rate of OPV has been proven by its widespread use in countries around the world. The reaction after vaccination is mild. Only some children have low fever, nausea, vomiting, rash or mild diarrhea 1-2 days after vaccination, and the symptoms will heal on their own after 2-3 days. Generally no medical treatment is required, but symptomatic treatment can be given if necessary. If the diarrhea is severe, it can be treated with antidiarrheal drugs, and antibiotics or sulfonamides are usually not needed. In very rare cases of allergic reactions after vaccination, it is generally difficult to determine whether they are related to OPV. Instead, they are related to the adjuvants (milk, cream) in the vaccine and can be treated symptomatically according to the situation.

Adverse reactions to polio vaccination are extremely rare. However, a very small number of OPV vaccine recipients or their contacts may develop vaccine-associated poliomyelitis paralysis (VAPP) due to low immunity, with an incidence of approximately 1/2.4 million doses (WHO statistics).

Common adverse reactions to IPV include: local reactions at the injection site, pain, erythema (redness of the skin), nodules; and moderate, transient fever. Very rare adverse reactions include: local swelling and lymphadenopathy at the injection site; allergic reactions such as urticaria, angioedema, and anaphylactic shock; moderate, transient joint pain and myalgia may occur; convulsions (with or without fever) may occur, and headache, moderate and transient paresthesia (mainly in the lower limbs) may occur within two weeks after vaccination; excitement, drowsiness, and irritability may occur in the first few hours or days after vaccination, but will disappear naturally soon; widespread rash; extremely premature infants (gestational age not exceeding 28 weeks) may experience apnea.