A brief discussion on the causes of gallbladder cancer

Gallbladder cancer ranks first among malignant tumors of the gallbladder, but it has not attracted enough attention for a long time. However, more and more people have realized the terribleness of gallbladder cancer. Let's talk about what causes gallbladder cancer.

The cause of gallbladder cancer is still unclear. Clinical observation shows that gallbladder cancer often coexists with benign gallbladder diseases, the most common of which is gallstones.

Most people believe that chronic stimulation of gallstones is an important pathogenic factor of gallbladder cancer.

Experts point out that 3.3% to 50% of patients with "hidden stones" will develop gallbladder cancer 5 to 20 years later. Domestic bulk data report that 20% to 82.6% of gallbladder cancers are complicated by gallstones, while foreign reports show that the rate is as high as 54.3% to 100%.

The occurrence of gallbladder cancer is closely related to the size of gallstones. The probability of cancer is 1.0 for gallstones with a diameter of less than 10 mm, 2.4 for gallstones with a diameter of 20 to 22 mm, and up to 10% for gallstones with a diameter of more than 30 mm. Others have suggested that the occurrence of gallbladder cancer may be related to the malformation of the lower end of the common bile duct and the main pancreatic duct. Due to this malformation, pancreatic juice enters the bile duct, increasing the concentration of pancreatic juice in the bile, causing chronic inflammation of the gallbladder, changes in the mucosa, and finally cancer.

Through the above explanation, I believe that everyone has a certain understanding of the cause of gallbladder cancer. I hope that after reading this article, everyone can pay more attention to gallbladder cancer. Here I would like to remind everyone that friends who suffer from gallbladder cancer, please go to the relevant regular hospital for treatment in time. This article is for reference only. If you have other questions, please consult our experts online.

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