There are many causes of lung cancer, including smoking, radiation, occupational and environmental exposure, air pollution, and chronic lung infection. Understanding the causes of lung cancer is helpful to understand the pathogenesis of lung cancer. There are four pathogenesis of lung cancer. Let's take a look at the pathogenesis of lung cancer. The pathogenesis of lung cancer: lymphatic metastasis. The lymphatic drainage of the lungs has a certain pattern. The right upper lobe flows to the right hilum and right upper mediastinal lymph nodes. The right middle lobe flows to the middle and lower lobe aggregation lymph nodes, the subcarinal process and the right upper mediastinal lymph nodes. The right lower lobe is induced to the middle and lower lobe aggregation area, the subcarinal process, the lower pulmonary ligament and the right upper mediastinal lymph nodes. The left upper lobe is induced to the subaortic arch (Bottallo) lymph nodes and the left anterior superior mediastinal lymph nodes. The left lower lobe lymph flows to the upper and lower lobe aggregation area, the subcarinal process and across the mediastinum to the right upper mediastinal lymph nodes. If the Cheng Maoshaofu's lymph node diagram (Figure 1) is used, the lymph node metastasis (N status) of lung cancer can be displayed. The second pathogenesis of lung cancer: lymphatic metastasis. Hematogenous metastasis is a late manifestation of lung cancer. After the cancer cells return to the left heart through the pulmonary veins, they can metastasize to any part of the body. Common metastatic sites are the liver, brain, lungs, bone system, adrenal glands, kidneys and pancreas. The third pathogenesis of lung cancer: direct spread. The tumor continues to grow and can block the bronchial lumen, while also expanding into the lung tissue outside the bronchus. Tumors near the periphery of the lung can invade the pleura and chest wall, and central tumors or tumors near the mediastinum can invade the pleura and chest wall. Central tumors or tumors near the mediastinum can invade other organs. Huge tumors can cause ischemic necrosis in the central part, forming a cancerous cavity. Pathogenesis of lung cancer 4: intrabronchial dissemination. In the case of alveolar cell carcinoma, cancer cells on the bronchioles and alveolar walls are easily detached; cancer cells can spread through the bronchial ducts to the adjacent lung tissues, forming new cancer foci. In summary, the pathogenesis of lung cancer includes four types: lymph node metastasis, lymph node metastasis, direct spread and intrabronchial dissemination. Understanding the pathogenesis of lung cancer will help to improve the treatment of lung cancer. Lung cancer topic: http://www..com.cn/zhongliu/fa/ |
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