What are the main causes of bone cancer

Bone cancer mainly refers to the skeletal system, which, like other organs, can suffer from tumors from any tissue components or metastatic lesions from other organs. However, many people do not know much about bone cancer, so they naturally do not understand the cause of bone cancer very clearly. Let us explore this aspect of bone cancer together.

1. The mechanism of bone cancer pain caused by bone metastasis comes from the chemical and mechanical stimulation of tumor cells on the nociceptors on the bone or periosteum, as well as the pain caused by tumor infiltration of sensory nerves. It is generally believed that bone destruction caused by tumors, pathological fractures, involvement of the periosteum, nerve infiltration, and activation of nociceptors by transmitters released by tumors are all causes of acute bone cancer.

2. When bone cancer destroys bone, it produces prostaglandin E1 and prostaglandin E2, which can sensitize peripheral nerve endings; this persistent pain can cause sensitization of nociceptors, and clinically, bone cancer manifests as abnormal pain and hyperalgesia. Therefore, this is also one of the causes of bone cancer.

The above are some of the most common causes of bone cancer. I hope it can help you learn more about bone cancer to a certain extent. If you have other questions about bone cancer, you can contact our online experts to answer your questions.

For more information, please visit the bone cancer disease special topic at http://www..com.cn/zhongliu/guai/ or consult an expert for free. The expert will then give a detailed answer based on the patient's specific situation.